LUPUS Flashcards
1
Q
morbidity and mortality is markedly higher in _____?
A
blacks and latinos
2
Q
SLE classification criteria?
A
malar rash discoid rash photosensitivity oral ulcers arthritis serositis
renal disorder neurologic disorder hematologic disorder immunologic disorder antinuclear antibody
- alopecia, follicular plugging, livedo reticularis, vesicular rash too
- *subacute cutaneous lupus associated with anti-Ro antibodies
3
Q
this is the leading determinant of morbidity and mortality in SLE?
A
renal disease
4
Q
nervous system disorders in SLE?
A
seizures, headaches, stroke syndromes, transverse myelitis, coma, dementia, ataxia, rigidity, chorea, aseptic meningitis, psychiatric disorders
5
Q
major indications of SLE from tests?
A
antibodies, like anti smith, anti ds DNA
immunologic disorders and antinuclear antibody tests can indicate SLE
6
Q
lupus like syndrome from drugs implicated in induction?
A
common: procainamide and hydralazine
rare: beta blockers, D-penicillamine
7
Q
patients with SLE have an increased risk of developing this condition of the vessels?
A
atherosclerosis
8
Q
treatment?
A
NSAIDs corticosteroids hydroxychloroquine azathioprine cyclophosphamide
other: mycophenylate mofetil methotrexate IVIG Belimumab
