SECONDARY LYMPHOID ORGAN Flashcards

1
Q

Upon the release of mature lymphocytes from primary lymphoid organs, they make their way to what organs?

A

Spleen
Lymph nodes
CALT
MALT

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2
Q

The migration is complex, therefore they are regulated by?

A

Cell surface adhesion marker
Cytokines

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3
Q

This organ is the 2nd larges lymphoid organ that is located on the upper left quadrant of the abdomen

A

Spleen

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4
Q

What is the function of the spleen?

A

To filter any old and damaged cells and Ag.

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5
Q

The spleen is divided into 2 sections. What are these?

A

Red pulp and White pulp

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6
Q

1/2 of the organ; RBC lysis

A

Red pulp

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7
Q

~20% of the organ; contains lymphoid tissue

A

White pulp

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8
Q

In the spleen why there is no need for the dendritic cells to present Ag?

A

Because the spleen is highly vascularized

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9
Q

How many mL of blood is supplied to the spleen every minute?

A

350mL

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10
Q

This organ collects and filters lymph

A

Lymph nodes

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11
Q

Sinuses are lined with _______?

A

Abundant macrophages

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12
Q

Cortex contains a ______________ and ___________ and follicular dendritic cells?

A

Macrophage
Naive B cells

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13
Q

Secondary follicles contain __________?

A

Active B cell

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14
Q

Medulla contains some _____________, ______________ and ___________.

A

T and B cells
Macrophages
Plasma cells

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15
Q

This is a condition where the fluid is accumulated

A

Lymphadenopathy

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16
Q

This structure is distributed all throughout the body where mucosal linings are present

A

MALT

17
Q

What are the classifications of MALT?

A

GALT
BALT
CALT

18
Q

These are the lymphoid tissues that are found on GIT?

A

GALT

19
Q

These are lymphoid tissues that are found in the Lower RT?

A

BALT

20
Q

This is situated in the skin layers (epidermis) interacts with lymphocytes in the skin

A

Langerhans’ cells

21
Q

What are the other SLO?

A

Tonsils, Appendix and Blood

22
Q

This is considered before as vestigial organ

A

Appendix

23
Q

This is where lymphocytes lives

A

Blood

24
Q

Progenitors appear as early as?

A

8 weeks (Age of Gestation)

25
Q

The progenitor cells of lymphocytes will come from the liver as part of _______________________________?

A

Fetal hematopoietic development