SECONDARY LYMPHOID ORGAN Flashcards
Upon the release of mature lymphocytes from primary lymphoid organs, they make their way to what organs?
Spleen
Lymph nodes
CALT
MALT
The migration is complex, therefore they are regulated by?
Cell surface adhesion marker
Cytokines
This organ is the 2nd larges lymphoid organ that is located on the upper left quadrant of the abdomen
Spleen
What is the function of the spleen?
To filter any old and damaged cells and Ag.
The spleen is divided into 2 sections. What are these?
Red pulp and White pulp
1/2 of the organ; RBC lysis
Red pulp
~20% of the organ; contains lymphoid tissue
White pulp
In the spleen why there is no need for the dendritic cells to present Ag?
Because the spleen is highly vascularized
How many mL of blood is supplied to the spleen every minute?
350mL
This organ collects and filters lymph
Lymph nodes
Sinuses are lined with _______?
Abundant macrophages
Cortex contains a ______________ and ___________ and follicular dendritic cells?
Macrophage
Naive B cells
Secondary follicles contain __________?
Active B cell
Medulla contains some _____________, ______________ and ___________.
T and B cells
Macrophages
Plasma cells
This is a condition where the fluid is accumulated
Lymphadenopathy