Schizophrenia

Question 1

positive symptoms of schizophrenia

Answer 1

hallucinations, delusions, agitation, tension, exaggeration or distortion or normal function

Question 2

negative symptoms of schizophrenia (presentation)

Answer 2

lack of motivation, blunted affect, poor self-care, social withdrawal, poverty of speech

Question 3

example of a low potency antipsychotic

Answer 3

thorazine

Question 4

example of a high potency antipsychotic

Answer 4

Haldol

Question 5

first generation antipsychotic mechanism of action

Answer 5

blocks dopamine2 receptors in brain

Question 6

first generation antipsychotic adverse effects

Answer 6

Extrapyramidal symptoms: acute dystonia, oculogyric crisis (eyes stay upward), joint dislocation, impaired respiration, opisthotonus (severe hypertension of neck)

Question 7

Along with EPS, what other adverse effects do you have to watch out for with antipsychotics

Answer 7

agranulocytosis (so do a CBC!), sexual dysfunction, severe dysrhythmias (so do an EKG prior to therapy!), neuroendocrine effects (increase levels of prolactin causes gynocomastia and galctorea and it doesnt go away)

Question 8

FG vs SG antipsychotic adverse effects

Answer 8

FG: Extrapyramidal symptoms, hypotension, cardiac problems, agranulocytosis

SG: metabolic issues: weight gain, diabetes, dyslipidemia, orthostatic hypotension, agranulocytosis