cholesterol

Question 1

HMG-CoA reductase inhibitors adverse effects

Answer 1

myopathy, hepatotoxicity

Question 2

Bile acid sequestrants adverse effects

Answer 2

GI distress, decrease in vitamin absorption

Question 3

Niacin adverse effects

Answer 3

flushing, hyperglycemia, hyperuricemia, hepatotoxicity,, upper GI distress

Question 4

Fibrates adverse effects

Answer 4

dyspepsia, gallstones, myopathy

Question 5

HMG-CoA reductase inhibitors contraindications

Answer 5

liver disease, pregnancy

Question 6

Bile acid sequestrants contraindications

Answer 6

dysbetalipoproteinemia, TG>400

Question 7

Niacin contraindications

Answer 7

liver disease, gout

Question 8

Fibrates contraindications

Answer 8

renal and liver disease

Question 9

Colesevelam, cchikestyramine and colestipol are which kids of med?

Answer 9

Bile acid sequestrants

Question 10

Gemfibrozil (lopid) and Fenofibrare (Tricor) are which kinds of med?

Answer 10

Fibrate

Question 11

Fibrates and warfarin interaction

Answer 11

increases risk for bleeding

Question 12

can you combine bile acid sequestrants with a statin?

Answer 12

yes

Question 13

can you combine fibrates with a statin?

Answer 13

no just fibricor

Question 14

VLDL

Answer 14

deliver TG from liver to tissue and muscle

Question 15

LDL

Answer 15

deliver cholesterol to nonhepatic tissues

Question 16

apoliporoteins

Answer 16

increase structural stability of lipoproteins, activate enzymes that metabolize lipoproteins and allow cells to bind with and ingest lipoproteins

Question 17

who would benefit from a statin? (4)

Answer 17

• patients with ASCVD
• patients with LDL >190
• 40-75 year old diabetics with LDL 70-189
• 40-75 year old no ASCVD or non diabetics with LDL 70-189 and a ASVD risk of 7.5%

Question 18

metabolic syndrome

Answer 18

metabolic abnormalities associated with an increased risk for ASCVD and type 2 diabetes