OC/SERMS Flashcards
Selective Estrogen Receptor Modulators (SERMS) help with what?
used to help osteoporosis and vaginal dryness, LDLs
Tamoxifen, toremifene, raloxifene
Selective Estrogen Receptor Modulators (SERMS)
How does Tamoxifen (an SERM) help in breast cancer treatment
it inhibits cell growth in the breast
women who are at risk for a STD should not use which method of contraception?
IUD
Absolute contraindications for oral contraceptives
Thrombophlebitis, cerebral vascular disease, abnormal liver function breast cancer undiagnosed vaginal bleeding pregnancy smoker over 35 HTN
Estrogen function in OC
inhibits release of FSH
Progesterone function in OC
inhibits release of LH surge
when should OC be stopped before surgery
4 weeks
what do OC protect against and what do they have no effect on?
protect against ovarian and endometrial
no effect on cervical
If HTN occurs while on OC what do you do?
DC OC and take care of HTN or just DC OC
mestranol in OC can cause what complication
hepatic adenoma
Too much estrogen can cause?
nausea, breast tenderness, and edema
Too much Progestin can cause?
increase in appetite, fatigue, depression
which meds decrease OC effects
st jons wart, seizure meds, TB meds, ritonavir (HIV meds)
OC effect on warfarin
it decreases effect of warfarin
positives about progestrin only pills and negative
no blood clot worries, headaches, nausea that you would get with estrogen, slow movement of ovume through fallopian tubes they cause more breakthrough bleeding, and increased risk for etopic pregnancy and ovarian cysts
Lo loestrin Fe, Aviane, Gildess are examples of which kinds of OC?
monophasic
Necon 10/11, Azurette, Pimtrea are examples of which kinds of OC
biphasic
Caziant, Cyclessa, are examples of which kinds of OC
triphasic
what is unique about extended-cycle and continuous schedules? Why don’t you need to have a monthly bleed with this OC? Who are these good for?
they suppress endometrial thickening, good for women who have migraines associated with their period
Amethia, Camrese and Lybrel are examples of which kind of OC
extendend-cycle
what is levonorgestrel and what is it found in?
progestrone and it is the main ingredient in Plan B
Biphasic OC, how is estrogen effected, how is progestin effected?
two pill strengths, amount of estrogen remains the same, progestrone lower in first 10 days
why were triphasic and quadriphasic formulations of OC invented?
to decrease total monthly dose of progestin and reduce adverse effects
Camila, Errin, Heather are which type of OC?
progestrin-only
Selective Estrogen Receptor Modulators (SERMS) function
drugs that activate estrogen receptors in some tissues and block them in others
activation of estrogen receptors fromSelective Estrogen Receptor Modulators (SERMS) can cause good effects and bad effects, bad effects?
increase risk for endometrial cancer, thromboembolism
