Diuretics

Question 1

Can loop diuretics be administrated to patients with renal failure?

Answer 1

yes

Question 2

which diuretics cant be administered to patients with renal failure?

Answer 2

thiazide

Question 3

loop vs thiazide

Answer 3

loop= works for renal failure patients
thiazide=doesn’t work for renal failure

loop=acts earlier in the system which produces more urine
thiazide=acts later in the system which produces less urine

loop=causes ototoxicity
thiazide=doesn’t cause ototoxicity

loop=decreases BP drastically
thiazide=used for BP

Question 4

where does thiazide act on?

Answer 4

Early distal convoluted tubules

Question 5

How do loop and thiazides effect electrolytes (Na, Chloride and K, lipids, mag, BS, uric acis)

Answer 5

hyponatremia, hypochloremia, hypokalemia, increases lipids, deceases mag, increase in BS

Question 6

which BP meds should you avoid with spironolactone and why?

Answer 6

ACE, ARB because they can increase K

Question 7

How does spironolactone effect the endocrine

Answer 7

its a steroid derivative so it can cause gynecomastia, menstrual irregularities, impotence, hirsutism, deepening of the voice