CCB Flashcards
which CCB act on peripheral arterioles and arteries and arterioles of the HEART?
Diltiazem and Verapamil
CCB function
dilate peripheral arterioles, increase heart perfusion, decrease in HR, decrease AV node conduction, decrease heart contraction
Verapamil therapeutic uses
angina, HTN, cardiac dysrhythmias
Verapamil adverse effects
constipation, gingival hyperplasia, 2nd and 3rd AV blocks
Verapamil drug interactions
increases Dig levels, grapefuit increases CCB effects
which HTN drugs should be avoided with verapamil and why?
BB because a BB can intensify the adverse effects of verapamil and Diltiazem
which patients should NOT take Verapamil?
sick sinus syndrome, Cardiac failure, 2nd and 3rd AV block
Does Nifedipine have an effect on heart?
no
Nifedipine therapeutic uses
angina, HTN
Verapamil vs Nifedipine
Verapamil decreases HR, decreases contractile force, used to correct cardiac dysrhythmias
Nifedipine increases HR, increases contractile force, not effective for dysrhythmias
which drug is used to decrease Nifedipine adverse effects (increased HR)
BB
CCB uses except for Nifedipine
Angina, HTN, cardiac dysrhythmias, renal disease, asthma, diabetes