musculokeletal

Question 1

DMARDS

Answer 1

reduce joint destruction and slow disease progression

Question 2

methotrexate and Sulfasalazine

Answer 2

nonbiological DMARDS

Question 3

what lab tests are mandatory when taking methotrexate?

Answer 3

liver and kidney function tests, CBC

Question 4

methotrexate adverse effects

Answer 4

Hepatic fibrosis, bone marrow suppression, GI ulceration and pneumonitis

Question 5

what do you give methotrexate with to decrease liver and GI problems?

Answer 5

folic acid

Question 6

Tumor Necrosis Factor inhibitor (TNF) action

Answer 6

neutralize TNF which in turn helps stop joint injury

Question 7

major serious infections with Tumor Necrosis Factor inhibitors (TNF)

Answer 7

bacterial sepsis, invasive fungal infections, hep B, TB

Question 8

Tumor Necrosis Factor inhibitors (TNF) are contraindicated in patients with which diseases?

Answer 8

severe heart failure, HBV, TB

Question 9

examples of Tumor Necrosis Factor inhibitors (TNF)

Answer 9

Etanercept, humira, Remicade

Question 10

which kind of people get bisphosphonates

Answer 10

postmenopausal osteoporosis, osteoporosis, osteoporosis in men, glucocorticoid-induced osteoporosis, hypercalcemia of malignancy, paget disease

Question 11

bisphosphonates function

Answer 11

inhibit bone reabsorption

Question 12

bisphosphonates adverse effects

Answer 12

ocular inflammation, osteonecrosis of jaw, femur fractures, afib

Question 13

Actonel, Boniva, Evista are examples of what?

Answer 13

bisphosphonates