sarcomas (bone and soft tissue) Flashcards
_______ occur in extraskeletal connective tissues that provide connection, support, and movement
Soft tissue sarcomas (STS)
Common cells in the connective tissues are the
mesoderm, primitive mesenchyme, and ectoderm
_____ Arise in structures that have connective tissues like blood vessel walls, pleura, pericardium, endothelium of blood vessels, bone, cartilage, muscles, and soft connective tissues
sarcomas
Soft tissue sarcomas mostly occur in ____in adults
extremities
Soft tissue sarcomas mostly occur in the_____ for Children
trunk, head, and neck
Common symptoms of sarcomas are a
painless, enlarging mass
When irradiating sarcomas, it is important that the entire ______of the extremity or area is not within the treatment field
circumference
Sarcomas are named by the tissues they
occur in
The Most common sarcoma pathology in adults is
malignant fibrous histiocytomas (MFH)
Most common sarcoma pathology in children is:
rhabdomyosarcoma
_____ is a:
Rhabdomyosarcoma
Highly malignant tumors in the skeletal muscles that can occur in any location of the body
Rhabdomyosarcoma
Subtypes of Rhabdomyosarcoma include
embryonal (most common), alveolar, pleomorphic/anaplastic, mixed type, and spindle cell
Most common site of rhabdomyosarcoma is the
genitourinary tract
kidneys, ureters, bladder, urethra, and genital organs
rhabdomyosarcoma typically occurs between the ages of
0 to 19
Osteosarcoma occurs in
osteoblasts (immature bone) in osteoid tissue
Osteosarcoma Most frequently occurs in the __________ like the distal femur’ proximal tibia, or shoulder
metaphysis of extremities
Osteosarcomas are radio___
radioresistant
osteosarcomas typically occur between thr ages of
10-19
______ is the second most common bone tumor
Ewing’s sarcoma
Ewing’s sarcoma: occurs most frequently in the
diaphysis of the femur
Ewing’s sarcoma Has an _____appearance on radiographic images
onion-shaped
Ewing sarcoma is More common in children and adolescents ____than the age of 19
younger
______ are tumors of the cartilage
Chondrosarcomas
Chondrosarcomas most commonly occur in the
pelvis, upper leg, and shoulder
Chondrosarcomas are most common in adults over the age of
40
Chondrosarcomas aggressively spread to
local areas
soft tissue sarcoma etiology
- direct cause is unknown
- genetic and environmental factors such as previous radiation, herbicide exposure
