Leukemia Flashcards
______develops during the formation of blood and lymphocytes pluripotent stem cells form into erythrocytes, neutrophils, eosinophils, basophils, monocytes, platelets, or lymphocytes
Leukemia
With leukemia, hematopoietic or lymphopoietic production is
uncontrolled and accelerated
Leukemic cells build up in the bone marrow, which can affect the production of
red blood cells, white blood cells, and platelets
What staging does leukemia cancer use
FAB (French, American, British)
A common treatment for leukemia is _________ which require require total body irradiation (TBI)
bone marrow transplant
______ is a overgrowth of unhealthy lymphoblasts, B lymphocytes, or T lymphocytes which limits the growth of healthy cells
ALL (Acute Lymphocytic Leukemia)
ALL (Acute Lymphocytic Leukemia) is the most common
pediatric disease
ALL (Acute Lymphocytic Leukemia) most commonly occurs in ages
2-3
______is a Overgrowth of cells that are unable to differentiate in response to hormonal signals and cellular interactions
AML (Acute Myelogenous Leukemia)
AML (Acute Myelogenous Leukemia) is the most common type of
acute leukemia in adults
AML (Acute Myelogenous Leukemia) patients are typically older than
40
AML (Acute Myelogenous Leukemia) is diagnosed because
Auer rods are present in leukemic cells
_________ is an Increased number of leukemic cells in the bone marrow, blood, lymph nodes, and spleen
CLL (Chronic Lymphocytic Leukemia)
For CLL (Chronic Lymphocytic Leukemia) bone marrow function is
lessened
CLL (Chronic Lymphocytic Leukemia) is ____% of all leukemias
30%
Risk of developing CLL (Chronic Lymphocytic Leukemia) increases with
age
FOr CLL (Chronic Lymphocytic Leukemia) _____ is not a risk factor
exposure to radiation
______ is an Abnormal hematopoietic stem cells that contain the Philadelphia chromosome (Phil)
CML (Chronic Myelogenous Leukemia)
CML (Chronic Myelogenous Leukemia) increases
granulocytes and megakaryocytes
CML (Chronic Myelogenous Leukemia) is common in age
mid-60
there are three stages of CML (Chronic Myelogenous Leukemia) which are
chronic, accelerated, and blast crisis
Bone Marrow Transplant (BMT) is main treatment for
ALL, AML, CML
__________ is where Healthy bone marrow is taken from an appropriate donor and is then introduced into the patient who has diseased bone marrow that has been destroyed by chemotherapy or total body irradiation (TBI)
Bone Marrow Transplant (BMT)
Who are the best donors for Bone Marrow Transplant (BMT)
Identical twins - Syngenic
______BMT; the patient’s own bone marrow is reinfused after leukemic cells have been removed
Autologous
______BMT: bone marrow is donated by a compatible donor (family member or stranger)
Allogeneic
