pharynx, larynx Flashcards

1
Q

What are the three subdivisions of the pharynx

A

nasopharynx, oropharynx, laryngopharynx/hypopharynx

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2
Q

______ is
-Cuboidal in shape
- Positioned posterior to the nose and extends inferiorly to the Uvula
- Located at Level of C1

A

Nasopharynx

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3
Q

Cancers in the _____have symptoms, such as consistent sore throat, pain while swallowing, pain in the ear, and cervical node enlargement

A

pharynx

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4
Q

Adenoids are located within the

A

nasopharynx

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5
Q

Nasopharynx is located close to the base of the

A

brain

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6
Q

_____usually occur in the lateral walls of the nasopharynx

A

carcinomas

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7
Q

There is a strong connection between nasopharyngeal cancers and the

A

Epstein. Barr virus (EBV)

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8
Q

Oropharynx is Positioned posterior to the oral cavity and extends from the

A

soft palate (Superiorly) to the hyoid bone (inferiorly)

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9
Q

________ is
located at level C2 to C3
Contains lymphoid tissue called palatine tonsils

A

Oropharynx

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10
Q

Most cancers in the oropharynx occur in the

A

tonsils

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11
Q

Oropharynx is Associated with

A

alcohol consumption, smoking, and HPV

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12
Q

The Laryngopharynx extends from the

A

hyoid bone to esophagus

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13
Q

_____ is
- located C3 to C6
- Posterior to larynx
- Made up of the pyriform sinuses, postcricoid and lower posterior pharyngeal walls

A

Laryngopharynx

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14
Q

The _____ is the superior border of the laryngopharynx at the level of C3

A

epiglottis

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15
Q

_______ is the most common location for cancer within the hypopharynx

A

Pyriform sinus

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16
Q

Majority of pharynx cancers have what histology

A

squamous cell carcinoma (SCC)

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17
Q

_______drains to subdigastric, upper cervical, submaxillary and parapharyngeal nodes

A

Oropharynx

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18
Q

_____drains to cervical nodes, retropharyngeal node (node of Rouviöre), and jugulodigastric nodes

A

Nasopharynx

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19
Q

______drains to midcervical nodes, superior deep, middle and low jugular nodes; and retropharyngeal node (node of Rouviöre)

A

Hypopharynx

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20
Q

Oropharynx tumors spread to lymph nodes and invade structures located

A

close to the tumor

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21
Q

The hypopharynx commonly spreads to lymph nodes and invades

A

nerves and muscles nearby

22
Q

The _____ extend from the epiglottis to the cricoid cartilage

23
Q

Cancer in the larynx is strongly associated with

A

cigarette smoking

23
Q

The larynx is located at the level of

24
Common symptoms of larynx cancer is
constant soreness of the throat and hoarseness
24
The larynx includes the
supraglottis, glottis, and subglottis
25
_____ = epiglottis, false vocal cords, ventricles, aryepiglottic folds, arytenoids
Supraglottis
26
____ = true Vocal cords and anterior/posterior commissures
glottis
27
_____ = 1 cm below true Vocal cords
subglottis
28
Supraglottic cancers spread first to what nodes?
jugulodigastric and midjugular nodes
28
What is most common histology of larynx cancer
squamous cell carcinoma
29
Glottic cancers rarely spread to
lymph nodes
30
Subglottic cancers spread first to what nodes?
pretracheal, paratracheal, and inferior jugular nodes
31
what is the clinical presentation for nasopharynx
- blood discharge - auditory dysfunction - respiratory dysfunction -cranial nerve involvement -squamous cell carcinoma most common
32
detection and diagnosis for nasopharynx
- history and physical - inspection - indirect mirror examination - palpation - biopsy - fiber optic endoscopy - CT/MRI - EBV - specific serologic test - liver function test/ bone scans with advanced disease
33
what is treatment for nasopharynx?
- opposing lateral fields to cover tumor and possible pathways of spread - supraclavicualr area treated - IMRT replacing most treatemtns
34
typical dose scheme for nasopharynx
50-70 Gy with electron boost and special consideration to - spinal cord, optic nerve and pituitary and brainstem
35
radiation treatment border for nasopharynx
Superior - 2 cm beyond tumor (seen on Ct) to include base of skull and sphenoid sinuses Posterior - 2 cm margin beyond mastoid process or posterior margin may extend further to allow 1.5 cm margin on enlarged nodes anterior - to include the posterior third of the maxillary sinus and nasal cavity, careful attention adequate margin (2cm) for more anterior tumors inferior - thyroid notch to allow sparing of larynx lower neck - anterior supraclavicular field with larynx block
36
clinical presentation for oropharynx
- sore throat - pain or swallowing - upper spinal nodal swelling - referred otalgia - squamous cell carcinoma most common
37
detection and diagonosis oropharynx (tonsils)
direct inspection palpation biopsy
38
treatment for oropharynx
T1-T2 soft palate, tonsil , pharyngeal walls , tongue: 66-70 Gy T3-T4 - oropharygeal and T2 base of tongue 70-81.6 Gy hyper fractionation - 70 Gy
39
radiation treatment border oropharynx (tonsils)
anterior - 2 cm from known tumor superior - 1.5 - 2.0 cm superior to the soft palate posterior - posterior spinous process inferior - level of hyoid
40
clinical presentation for hypohphraynx
- sore throat - odynophagia - neck mass - dysphagia - weight loss - squamous cell carcinoma most common
41
detection and diagnosis for hypopharynx
- inspection - palpation - biopsy - fiber optic endoscopy - CT/MRI
42
treatment for hypopharynx
large fields treated to 45 Gy reduced of cord then continued to 70 Gy
43
treatment borders hypopharynx
superior - inferior border of mandible and mastoid process, to the base of skull inferior - lower border of the cricoid cartilage 1.5 to 2.0 cm margin anterior - in front of the thyroid cartialge "shine off" (fall off) if larynx involved posterior - behind the spinous process
44
larynx is made up off :
glottis supraglottis and subglottis
45
larynx clinical presentation:
- persistent sore throat - hoarseness and stridor - cervial lymph node - supreglottic lesions - squamous cell carcinoma most common
46
detection and diagnosis for larynx
- palpation - direct inspection - biopsy
47
treatment for larynx
surgery chemo radiation therapy
48
radiation treatment borders for glottis
superior - upper thyroid notch inferior - cricoid cartilage (lower border of C6) anterior - 1-1.5 cm shine over (flash) over the skin surface at the level of the vocal cords posterior - just anterior to the vertebral body including the anterior portion of the posteiror pharyngeal walls
48
radiation treatment borders for supraglottis and subglottis
often much larger fields