Hodgkins lymphoma Flashcards

1
Q

The lymphatic system comprises lymphatic…

A

vessels, organs, and fluid called lymph

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2
Q

Functions of the ______system is to : drain interstitial fluid and filter foreign substances and cellular waste; absorb fats and transport them to the bloodstream; provide immunity to the body by trying to defend against infectious and foreign organisms

A

lymphatic

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3
Q

Lymphatic vessels eventually empty into the thoracic duct or the right lymphatic duct, Which then drains into the

A

subclavian veins

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4
Q

Lymphatic organs are the

A

spleen, thymus, tonsils, and thoracic duct

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5
Q

The ____is the largest of the lymphatic organs

A

spleen

others include
- blood
- bone marrow
- lymphatic tissue

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6
Q

______ are lymphatic tissue in the ileum on the small intestine

A

Peyer’s patches

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7
Q

T cells are in the

A

thymus

  • T cells : destroy germs
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8
Q

B cells are in the

A

bone marrow

  • B cells : create antibodies
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9
Q

For Hodgkin’s lymphoma: The _____cells are present in lymph nodes

A

Reed-Sternberg

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10
Q

Reed-Sternberg cells presence in lymph nodes determine whether lymphoma is

A

Hodgkin’s or non-Hodgkin’s lymphoma

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11
Q

Hodgkin’s lymphoma: is Associated with the

A

Epstein-Barr virus (EBV)

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12
Q

For Hodgkin’s lymphoma: it has a predictable, contiguous spread pattern throughout the

A

lymph

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13
Q

For Hodgkin’s lymphoma: it occurs in bimodal age-groups while are

A

25 to 30 years old and 75 to 80 years old

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14
Q

What are the B symptoms

A

Fever, night sweats, weight loss

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15
Q

Patients with B symptoms have a ___prognosis

A

worse

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16
Q

Chemotherapy used to treat Hodgkin’s lymphoma include :

A

MOPP (nitrogen mustard, vincristine sulfate [OncovinJ, procarbazine hydrochloride, and prednisone) and ABVD (adriamycin, bleomycin, vinblastine, and dacarbazine)

17
Q

Radiation therapy technique used For Hodgkin’s lymphoma is called the

A

mantle field

18
Q

___________has 4 subcategories: which are

A

Classic Hodgkin’s lymphoma (CHL)

19
Q

> > Lymphocyte-rich Hodgkin’s lymphoma (LRHL),

A

___________has 4 subcategories: which are

20
Q

> > nodular sclerosing Hodgkin’s lymphoma (NSHL),

A

most common subcategory

21
Q

> > mixed cellularity Hodgkin’s lymphoma (MCHL),

A

___________has 4 subcategories: which are

22
Q

> > lymphocytedepleted Hodgkin’s lymphoma (LDHL)

A

Classic Hodgkin’s lymphoma (CHL)

23
Q

What staging does Hodgkins use

A

Ann arbor

24
Q

For Hodgkin’s lymphoma: Staged as ___ if there are no general symptoms

A

A

25
Q

For Hodgkin’s lymphoma: Staged as __ if the patient experiences B symptoms

A

B

26
Q

For Hodgkin’s lymphoma: The diaphragm is used to divide

A

stages

27
Q

For Hodgkin’s lymphoma: Stages 1 and 2: disease is

A

above the diaphragm

28
Q

For Hodgkin’s lymphoma: Stages 3 and 4: disease is

A

below the diaphragm

29
Q

For Hodgkin’s lymphoma: Spread occurs to adjacent lymph nodes and to the spleen in

A

later stages

30
Q

when it comes to HL staging ____

A

has the greatest effect on the prognosis

  • as well as pretense of B symtoms
31
Q

clinical presentation for HL

A
  • painless mass in neck and supraclavicular area
  • mediastinal node - chest x-ray
  • most disease above disphragm
32
Q

when it comes to spread of lymphatic drainage and spread patterns for HL

A
  • spread is predictable referred to as contigous
33
Q

A common chemo combination used to treat HL is :

A

ABVD

  • Adriamycin bleomycin vinblastine and sacarbazine
34
Q

when it comes to HL certain radiation fields that can be used to treat it are:

A

Mantle field and inverted Y

35
Q

the mantle field treats lymph nodes in the

A

neck chest and axilla areas

36
Q

the inverted Y treats lymph nodes in the

A

abdomen and pelvis as well as spleen