Hodgkins lymphoma Flashcards
The lymphatic system comprises lymphatic…
vessels, organs, and fluid called lymph
Functions of the ______system is to : drain interstitial fluid and filter foreign substances and cellular waste; absorb fats and transport them to the bloodstream; provide immunity to the body by trying to defend against infectious and foreign organisms
lymphatic
Lymphatic vessels eventually empty into the thoracic duct or the right lymphatic duct, Which then drains into the
subclavian veins
Lymphatic organs are the
spleen, thymus, tonsils, and thoracic duct
The ____is the largest of the lymphatic organs
spleen
others include
- blood
- bone marrow
- lymphatic tissue
______ are lymphatic tissue in the ileum on the small intestine
Peyer’s patches
T cells are in the
thymus
- T cells : destroy germs
B cells are in the
bone marrow
- B cells : create antibodies
For Hodgkin’s lymphoma: The _____cells are present in lymph nodes
Reed-Sternberg
Reed-Sternberg cells presence in lymph nodes determine whether lymphoma is
Hodgkin’s or non-Hodgkin’s lymphoma
Hodgkin’s lymphoma: is Associated with the
Epstein-Barr virus (EBV)
For Hodgkin’s lymphoma: it has a predictable, contiguous spread pattern throughout the
lymph
For Hodgkin’s lymphoma: it occurs in bimodal age-groups while are
25 to 30 years old and 75 to 80 years old
What are the B symptoms
Fever, night sweats, weight loss
Patients with B symptoms have a ___prognosis
worse
Chemotherapy used to treat Hodgkin’s lymphoma include :
MOPP (nitrogen mustard, vincristine sulfate [OncovinJ, procarbazine hydrochloride, and prednisone) and ABVD (adriamycin, bleomycin, vinblastine, and dacarbazine)
Radiation therapy technique used For Hodgkin’s lymphoma is called the
mantle field
___________has 4 subcategories: which are
Classic Hodgkin’s lymphoma (CHL)
> > Lymphocyte-rich Hodgkin’s lymphoma (LRHL),
___________has 4 subcategories: which are
> > nodular sclerosing Hodgkin’s lymphoma (NSHL),
most common subcategory
> > mixed cellularity Hodgkin’s lymphoma (MCHL),
___________has 4 subcategories: which are
> > lymphocytedepleted Hodgkin’s lymphoma (LDHL)
Classic Hodgkin’s lymphoma (CHL)
What staging does Hodgkins use
Ann arbor
For Hodgkin’s lymphoma: Staged as ___ if there are no general symptoms
A
For Hodgkin’s lymphoma: Staged as __ if the patient experiences B symptoms
B
For Hodgkin’s lymphoma: The diaphragm is used to divide
stages
For Hodgkin’s lymphoma: Stages 1 and 2: disease is
above the diaphragm
For Hodgkin’s lymphoma: Stages 3 and 4: disease is
below the diaphragm
For Hodgkin’s lymphoma: Spread occurs to adjacent lymph nodes and to the spleen in
later stages
when it comes to HL staging ____
has the greatest effect on the prognosis
- as well as pretense of B symtoms
clinical presentation for HL
- painless mass in neck and supraclavicular area
- mediastinal node - chest x-ray
- most disease above disphragm
when it comes to spread of lymphatic drainage and spread patterns for HL
- spread is predictable referred to as contigous
A common chemo combination used to treat HL is :
ABVD
- Adriamycin bleomycin vinblastine and sacarbazine
when it comes to HL certain radiation fields that can be used to treat it are:
Mantle field and inverted Y
the mantle field treats lymph nodes in the
neck chest and axilla areas
the inverted Y treats lymph nodes in the
abdomen and pelvis as well as spleen
