RNAV: Paramyxoviridae Flashcards

1
Q

What subfamilies belong in the Paramyxoviridae family?

A

Paramyxoviridae
Rubulavirus
Pneumovirus
Morbillivirus
Henipavirus

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2
Q

What disease is most commonly caused by Parainfluenza Virus Type 1 and 2?

A

Croup (Laryngotracheobronchitis)

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3
Q

What disease is commonly caused by Parainfluenza Virus Type 3 in infants?

A

Bronchiolitis and pneumonia

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4
Q

What is a key distinguishing characteristic of Parainfluenza Virus Type

A

Most common cause of pneumonia and bronchiolitis in infants after Respiratory Syncytial Virus (RSV)

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5
Q

What disease is caused by Mumps Virus (Rubulavirus)?

A

Mumps, parotitis, orchitis, meningitis

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6
Q

How is Mumps Virus (Rubulavirus) transmitted?

A

Droplet spread, contact with saliva

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7
Q

What diseases are caused by Respiratory Syncytial Virus (RSV) (Pneumovirus) in infants?

A

Bronchiolitis, pneumonia, respiratory infections

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8
Q

What diseases are caused by Measles Virus (Rubeola) (Morbillivirus)?

A

Measles, encephalitis, pneumonia

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9
Q

What are some distinguishing characteristics of Measles Virus (Rubeola) (Morbillivirus)?

A

Causes Koplik spots, maculopapular rash, no neuraminidase

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10
Q

What are the important members of Henipavirus in the Paramyxoviridae family?

A

Nipah Virus (NiV)

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11
Q

What diseases are caused by Nipah Virus (NiV)?

A

Encephalitis, Acute Respiratory Illness, Severe Pneumonia

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12
Q

How is Nipah Virus (NiV) transmitted to humans?

A

Zoonotic (from bats to humans)
Direct contact with infected animals (pigs, bats)
Person-to-person via respiratory secretions

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13
Q

What are the distinguishing characteristics of Nipah Virus (NiV)?

A

High mortality rate (~40-75%)
Zoonotic origin
Can cause severe neurological and respiratory disease

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14
Q

What is the size and shape of Nipah Virus (NiV)?

A

150-300 nm, Pleomorphic, Enveloped

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