RNAV: Flaviviridae Flashcards
What are the subgroups that belong to the Flaviviridae family?
Arbovirus
Non-Arbovirus
What are the important members of the Arbovirus group?
Yellow Fever
Dengue Virus
West Nile
Zika Virus
Japanese Encephalitis
St. Louis Encephalitis
What are the important members of the Non-Arbovirus group?
Hepatitis C
How is the Yellow Fever Virus transmitted?
Mosquito bite (Aedes, Haemagogus)
What are the distinguishing characteristics of Yellow Fever Virus?
Infects liver, causes jaundice & hemorrhage, monkey serves as a reservoir
What disease is caused by Dengue Virus (DENV 1–4)?
Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
How is Dengue Virus (DENV 1–4) transmitted?
Mosquito bite (Aedes aegypti, Aedes albopictus)
What are the distinguishing characteristics of Dengue Virus (DENV 1–4)?
4 serotypes, causes ‘breakbone fever’ with severe muscle & joint pain
What diseases are caused by West Nile Virus (WNV)?
West Nile Fever, Encephalitis, Meningitis
How is West Nile Virus (WNV) transmitted?
Mosquito bite (Culex spp.), blood transfusion, organ transplant
What are the distinguishing characteristics of West Nile Virus (WNV)?
Maintained in bird-mosquito cycle, can cause neuroinvasive disease
What disease is caused by Zika Virus?
Zika Fever, Congenital Zika Syndrome
What is the size and shape of Arboviruses and Non-Arboviruses?
40–50 nm, Icosahedral, Enveloped
What is the mode of transmission for Zika Virus?
Mosquito bite (Aedes aegypti), Sexual transmission, Mother-to-fetus, Blood transfusion
What are the key characteristics of Zika Virus?
Can cause microcephaly in newborns, Linked to Guillain-Barré Syndrome
What is the mode of transmission for Japanese Encephalitis Virus?
Mosquito bite (Culex spp.)
What are the key characteristics of Japanese Encephalitis Virus?
Most common cause of viral encephalitis in Asia, High fatality rate
What is the mode of transmission for St. Louis Encephalitis Virus?
Mosquito bite (Culex spp.)
What are the key characteristics of St. Louis Encephalitis Virus?
Endemic in North America, Can cause severe central nervous system involvement
What disease is caused by Hepatitis C Virus?
Liver Cirrhosis
Hepatocellular Carcinoma
What is the mode of transmission for Hepatitis C Virus?
Bloodborne (Needles, Transfusion, Sexual transmission, Perinatal)
What are the key characteristics of Hepatitis C Virus?
Chronic infection common, Major cause of liver cancer
