DNAV: Parvoviridae Flashcards
What are the members of the parvoviridae family?
Parvovirus B19
Human Bocavirus (HBoV)
Human Bufavirus (HuBuV) or Parvovirus 4
What is another name for Parvovirus B19 infection?
Erythema infectiosum
Which childhood disease is caused by Parvovirus B19?
Fifth disease
What is the genome type of Parvovirus B19?
Single-stranded DNA
Which type of cells does Parvovirus B19 primarily infect?
Erythroid precursors
What is the only Parvovirus known to infect humans?
Parvovirus B19
What is the classic rash appearance in Parvovirus B19 infection?
Slapped-cheek rash
How long is the incubation period for Parvovirus B19?
4-14 days
When is a person with Parvovirus B19 most contagious?
Before the rash appears
What are the potential complications of Parvovirus B19 infection?
Arthritis, aplastic crisis, fetal loss
Is there a vaccine available for Parvovirus B19?
No
Which type of infections are associated with Human Bocaviruses?
Respiratory tract infections in children
What is the emerging significance of Human Bocaviruses?
Associated with upper and lower respiratory illnesses in pediatric patients
What is the known clinical significance of Human Bufaviruses and PARV4?
Unknown
In which patient population have Human Bufaviruses and PARV4 been detected?
Immunocompromised patients
What is the current level of research on Human Bufaviruses and PARV4?
Limited studies on their pathogenic roles