DNAV: Parvoviridae Flashcards

1
Q

What are the members of the parvoviridae family?

A

Parvovirus B19
Human Bocavirus (HBoV)
Human Bufavirus (HuBuV) or Parvovirus 4

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2
Q

What is another name for Parvovirus B19 infection?

A

Erythema infectiosum

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3
Q

Which childhood disease is caused by Parvovirus B19?

A

Fifth disease

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4
Q

What is the genome type of Parvovirus B19?

A

Single-stranded DNA

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5
Q

Which type of cells does Parvovirus B19 primarily infect?

A

Erythroid precursors

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6
Q

What is the only Parvovirus known to infect humans?

A

Parvovirus B19

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7
Q

What is the classic rash appearance in Parvovirus B19 infection?

A

Slapped-cheek rash

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8
Q

How long is the incubation period for Parvovirus B19?

A

4-14 days

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9
Q

When is a person with Parvovirus B19 most contagious?

A

Before the rash appears

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10
Q

What are the potential complications of Parvovirus B19 infection?

A

Arthritis, aplastic crisis, fetal loss

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11
Q

Is there a vaccine available for Parvovirus B19?

A

No

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12
Q

Which type of infections are associated with Human Bocaviruses?

A

Respiratory tract infections in children

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13
Q

What is the emerging significance of Human Bocaviruses?

A

Associated with upper and lower respiratory illnesses in pediatric patients

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14
Q

What is the known clinical significance of Human Bufaviruses and PARV4?

A

Unknown

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15
Q

In which patient population have Human Bufaviruses and PARV4 been detected?

A

Immunocompromised patients

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16
Q

What is the current level of research on Human Bufaviruses and PARV4?

A

Limited studies on their pathogenic roles