DNAV: Poxviridae Flashcards
What are the members that belong to the poxviridae family?
Variola (Smallpox)
Molluscum Contagiosum
Monkeypox
Orf Virus
Which laboratory technique is used to visualize Variola virus particles?
Electron microscopy
Which molecular method is commonly used for detecting Variola virus DNA?
Polymerase Chain Reaction
What is the envelope status of Variola virus?
Enveloped
What is the largest known DNA virus in terms of size?
Variola virus (200-450 nm)
What is the characteristic shape of Variola virus?
Brick-shaped/oval
Which disease was caused by Variola virus but has been eradicated?
Smallpox
Which laboratory technique is commonly used to confirm Molluscum contagiosum virus infection?
Polymerase Chain Reaction
What is the primary method of diagnosing Molluscum contagiosum virus infection?
Clinical diagnosis
What is the envelope status of Molluscum contagiosum virus?
Enveloped
Which characteristic skin lesion is caused by Molluscum contagiosum virus?
Small, pearly papules with a central core
Which population is most commonly affected by Molluscum contagiosum?
Children
Which two laboratory methods are used for detecting Monkeypox virus?
Polymerase Chain Reaction and cell culture
What is the envelope status of Monkeypox virus?
Enveloped
Which type of rash is characteristic of Monkeypox infection?
Vesicular-pustular rash
How is Monkeypox virus primarily transmitted to humans?
Zoonotic transmission
Which disease is caused by Monkeypox virus?
Monkeypox
Which molecular technique is used to diagnose Orf virus infections?
Polymerase Chain Reaction
What is the envelope status of Orf virus?
Enveloped
Which animals are the primary hosts of Orf virus?
Sheep and goats
Which type of lesions are caused by Orf virus in humans?
Nodular lesions on hands or fingers
Which occupational group is at higher risk for Orf virus infection?
Individuals with occupational exposure to infected animals (e.g., farmers, veterinarians)