RNAV: Filoviridae Flashcards
What are the important members of the Filoviridae family?
Marburg Virus
Ebola Virus
What diseases are caused by the Filoviridae family?
Marburg Virus Disease (MVD)
Ebola Virus Disease (EVD)
Hemorrhagic Fever
How is Marburg Virus Disease and Ebola Virus Disease transmitted?
Direct contact with infected bodily fluids
Contaminated objects
Animal reservoirs (Fruit bats for Marburg; Bats and non-human primates for Ebola)
What are the distinguishing characteristics of Marburg Virus?
Highly fatal hemorrhagic fever
Zoonotic (fruit bats as reservoir)
Person-to-person transmission possible
What are the distinguishing characteristics of Ebola Virus?
Causes severe hemorrhagic fever
High mortality rate
Multiple species (Zaire, Sudan, Bundibugyo, Tai Forest, Reston)
What is the size and shape of viruses in the Filoviridae family?
80-100 nm wide, Filamentous, Pleomorphic, Enveloped
What are the possible causes of infection with Filoviridae viruses?
Contaminated food products
Close contact with infected animals
Contact with infected animal’s bodily fluids
Contact with an infected person via bodily fluids
Burial ceremonies involving direct bodily contact with an infected person
What are the early symptoms of Filoviridae infections?
Fever, Chills, Headache, Sore throat, Weakness, Muscle aches
What are the severe symptoms of Filoviridae infections?
Diarrhea
Abdominal pain
Nausea, Vomiting
Rash
Severe hemorrhagic signs
Confusion
Seizures
Shock
Multiple organ failure
Death
What is the primary animal reservoir for Filoviridae viruses?
African fruit bats
Where does the name “Ebola Virus” originate from?
Named for the river in the Democratic Republic of Congo
Which species of Ebola Virus are responsible for outbreaks?
Ebola Virus Zaire (EBO-Z) – More virulent
Ebola Virus Sudan (EBO-S)
