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Microbiology > RNA Virus > Flashcards

RNA Virus Flashcards

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Biology 101 flashcards
1
Q

What are the types of Picornaviruses

A

Enterovirus
Rhinovirus
Hepatovirus
Cardiovirus
Aphthovirus

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2
Q

Hepatovirus example

A

Hepatitis A virus

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3
Q

Cardiovirus example

A

Encephalomyocarditis virus
Human porechovirus

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4
Q

Example of Apthovirus

A

Foot-hand-mouth virus

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5
Q

How is the genome of Picornaviruses

A

+ ss RNA — able to act as mRNA when it enters to cell

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6
Q

What is the major receptor for Poliovirus

A

CD155

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7
Q

What are the examples of Enterovirus

A

Poliovirus
Human Enterovirus A,E
Coxockieviruses A,B
Echoviruses

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8
Q

Examples of Rhinovirus

A

Human rhinovirus A,B

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9
Q

Whic family of viruses have Lytic Infection

A

Picornaviruses

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10
Q

Non-Enterovirus diseases

A

Coxcakievirus A
Coxcakievirus B
Echoviruses
Enterovirus 70
Enterovirus 71

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11
Q

Features of Enteroviruses

A

PH range 3-10
Small intestine is the major invasion site
Resistant to acidic pH
Replicate best at=37 Celsius

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12
Q

Features of Rhinovirus

A

Ph= 6-8
Sensitive to acidic pH
Optimally replicate at = 33 Celsius

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13
Q

Which Picornavirus cannot reach to stomach

A

Rhinovirus bc it is sensitive to the acidic pH

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14
Q

How is the transmission of Enteroviruses

A

Ingestion of fecally infected material
Respiratory route

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15
Q

Where does Enterovirus replicate at

A

Susceptible tissues of phayrinx or gut
Lymphoid tissue of the small intestine
Reticuloendothelial tissue

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16
Q

Where does Enterovirus gives rise to minor and major viremia

A

Minor= regional lymph node
Major= Reticuloendothelial tissue

17
Q

What is Poliomyelitis

A

Caused by Poliovirus( Enterovirus— Picornavirus)
3 stereotypes = PV1,PV2,PV3
Minimal heterotypic immunity
1 in 200 infections leads to irreversible paralysis
Vaccines = IPV, OPV

18
Q

What does Coxcakievirus A causes

A

Herpangina
Hem. Conjunctiva A24
Hand foot mouth disease

19
Q

What does Coxcakievirus B causes?

A

Myocarditis
Pericarditis

20
Q

What does Echovirus causes

A

Aseptic meningitis

21
Q

What does Enterovirus 70 causes

A

Hem. Conjunctivitis

22
Q

What does Enterovirus 71 causes

A

CNS disease
Hand foot mouth disease

23
Q

Features of Rhabdoviruses

A

Neurotropic virus
Enveloped
SsRNA

24
Q

How is the rabies best spreaded

A

When the bite of the infected animal is deep enough to allow the virus to reach the deep skeletal muscle.

25
Q

How is the transmission of Rhinovirus

A

Aerosols
Direct contact

26
Q

How is the genome of Rhabdoviruses

A

GpG
Bullet-shaped
Enveloped
M protein
N protein
L protein
P protein
Helical Nucleocapsid

27
Q

How is the Initial infection of Rhabdoviruses

A

Replication in muscle or subepi
Spreads to nerves by binding to Ach receptors

28
Q

What are the stages of Classical Rabies

A

Prodromal stage=fever,headache,malaise..
Sensory excitation stage=hyperactivity,hallucinations..
Coma and paralysis phase=paralysis and respiratory problems, death

29
Q

What is the post-exposure vaccine to Rabies

A

Human Diploid Cell Vaccination

30
Q

How is the genome of Reovirus

A

Non enveloped
DsRNA-segmented

31
Q

Which virus is the agents of Viral Gastroentritis in children

A

Rotavirus

32
Q

Features of Rotavirus

A

Very stable
Remain infective
Resistant to acidic pH
11 gene segments
Three concentric capsid

33
Q

Which viruses are in the family of Reovirus

A

Rotavirus
Orthoreovirus
Coltivirus
Orbivirus

34
Q

What are the gene segments of Rotavirus

A

VP7 — G glycoprotein —— Genotypes: G1P,G2P,G3P,G4P,G9P

VP4— P protease sensitive ——Serogroups: A,B,C,D,E,F (inner core structural proteins)

Microbiology (22 decks)

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