Pathogenesis Of Parasitic Disease Flashcards
Parasitic Infection?
Invasion of endogenous parasites( protozoa,helminths)
Parasitic disease?
Invasion and pathology produced by endoparasites
Parasitic infection?
External parasitism by ectoparasites (arthropods)
Definitive host vs intermediate host?
D: sexually mature,adult
I:development occurs but not an adult
Entry routes of an parasites?
Oral
Penetration of skin
Bite of an arthropods
Genital tract
Congenital
Blood transfusion
Important determinants for the pathogenesis of parasitic infection?
Size
Invasion
Reproduction
Nutrition
Residency
Immunological consequences
Infective dose and exposure
Penetration of anatomical barriers
What does large size provides to a parasite?
Prevent phagocytosis
Inability to induce inflammation resulting in ignorance
Several immunodominant antigens
Too many immunomodulatory antigens
Complement mediated lysis not effective
What does trypanosoma spp. uses as a nutrition
Pyruvate
What plasmodium spp. uses as nutrition
Hemozoin release
What hookworms use as a nutrition
Depletion of the iron