Reye's Syndrome

Question 1

A rare but serious condition that causes swelling in the liver and brain

Answer 1

Reye’s Syndrome

Question 2

It can occur at any age but usually affects children and teenagers after a viral infection, most commonly the flu or chickenpox

Answer 2

Reye’s Syndrome

Question 2

Reye’s Syndrome Clinical Staging System

Laboratory evidence of liver dysfunction, lethargic, sleepy

Answer 2

Stage 1

Question 2

Reye’s Syndrome Clinical Staging System

Deeply lethargic, combative, hyperventilation, hyperreflexia

Answer 2

Stage 2

Question 3

Reye’s Syndrome Clinical Staging System

Obtunded or in a light coma, decorticate rigidity

Answer 3

Stage 3

Question 4

Reye’s Syndrome Clinical Staging System

Deepening coma, seizure, decerebrate rigidity, loss of oculovestibular reflexes, fixed pupils

Answer 4

Stage 4

Question 5

Reye’s Syndrome Clinical Staging System

Seizures, deep coma, flaccid paralysis, absent deep tendon reflexes, respiratory arrest, fixed dilated pupils

Answer 5

Stage 5

Question 6

Take note

Answer 6

The use of aspirin during a viral illness has the most commonly link to Reye’s Syndrome (adult)

Question 7

MCAD

Answer 7

Medium-chain acyl-CoA Dehydrogenase

Question 8

Fatty acid oxidation disorder

Answer 8

MCAD Deficiency

Question 9

A group of inherited metabolic disorders in which the body is unable to break down fatty acids

This happen because an enzyme is missing or not working properly

Answer 9

MCAD Deficiency

Question 10

In people with a fatty acid oxidation disorder, _______ use during a viral illness is more likely to trigger symptoms of Reye’s Syndrome

Answer 10

Aspirin

Question 11

A _________ can determine if your child has a fatty acid oxidation disorder

Answer 11

Screening test