Myasthenia Gravis: Assessment and Diagnostic Findings

Question 1

Assessment and Diagnostic Findings

Answer 1

1. Acetylcholinesterase Inhibitor test
2. Serum Assay for circulating Anti-Acetylcholine Receptor
3. Ice test
4. Acetylcholine antibodies
5. Electromyography

Question 2

Administration of edrophonium chloride (Tensilon)

IV: 30 seconds after injection facial muscle weakness and ptosis should resolve for about 5 minutes

Atropine should be available (for allergic reactions)

Answer 2

Acetylcholinesterase Inhibitor test

Question 3

(+) MG if increased

Answer 3

Serum Assay for circulating Anti-Acetylcholine Receptor

Question 4

For pt with asthma or cardiac condition

Ice is held over the pt’s eye for 1 minute
- ptosis should be resolved

Answer 4

Ice Test

Question 5

Reduced response to electrical stimulation

Answer 5

Electromyography