regulation of stroke volume and heart rate Flashcards
regulation of heart rate
sympathetic and parasympathetic ( vagus)
increase in heart rate by sympathetic
increasing the slope and decreasing the time between action potential
target of sympathetic nervous system
produces noradrenaline and effects on the
adrenal medulla to produce adrenaline that acts on beta 1 receptors on the sinoatrial node
parasympathetic effect on heart rate
decreases heart rate , production of acetylcholine which acts on muscarinic receptors of the sinoatrial node.
decrease in the slope of action potential and hyper - polarisation of the action potential
decrease in heart rate
regulation of stroke volume
factors that affect end diastolic volume
factors that affect end systolic volume
preload
amount of blood present in the heart just before systole by passive filling
how does preload influence stroke volume
energy of contraction will be equal to the initial length of the heart muscle
factors that affect end diastolic volume
venous return
self regulation
increased venous return effect on the end diastolic volume
there is increased end diastolic volume
afterload
amount of blood during isovolumetric contraction ; the ;load at which the heart pumps against
factors that affect after - load
theory of the 3 pipes
factors that affect afterload
increase in resistance of the arterioles means there is pull of blood in the aorta which means there is alot pressure needed to just open the aortic valves , there is therefore less blood present to push the blood out of the heart hence lower stroke volume.
neural regulation of stroke volume
sympathetic nerve system which causes release of noradrenaline and circulates adrenaline form the adrenal medulla.
sympathetic effect on the myocytes( non pacemaker cells)
they bind on the beta 1 receptors of the myocytes which means they have a greater contractile effect
parasympathetic effect on the vagus nerve
Little effect
Probably because the vagus nerve does not innervate the ventricular muscle
summary of the regulation of stroke volume
preload
contractility
afterload
control of cardiac output
factors that affect stroke volume
factors that affect heart rate
causes of reduced total peripheral resistance
arteriolar dilation in the muscles
reduces afterload