mendelian and non-mendelian characteristics

Question 1

what are the characteristics of sickle cell disease

Answer 1

Pain+++​

Cold, dehydration, infections​

Jaundice, stroke, leg ulcers, eyes, kidneys​

African, Mediterranean, Middle-East, Indian​

Anaesthetic issues​

Question 2

what is the cause of sickle cell disease

Answer 2

abnormal point mutation gene

Question 3

what is cystic fibrosis disease

Answer 3

this is a disease caused by the mutation of the gene for the chloride channel in the lungs.

Question 4

difference between the normal CFTR channel and an abnormal CFTR channel.

Answer 4

mutant CFTR channel does not move chloride ions causing sticky mucus to build up on the outside of the cell.

Question 5

example of CFTR sequence

Answer 5

there is deletion of certain numbers in the genes coding

Question 6

what does the term affected mean

Answer 6

being a carrier and those with the disease
chance of being carrier is 2/3 chance of being affected is 1/4