oedema and congestion Flashcards
what is congestion ?
this is relative excessive blood in vessels in the tissue or organs
examples of congestion
deep vein thrombosis
hepatic cirrhosis
generalised acute congestion
congestive cardiac failure
what causes hepatic cirrhosis
liver damage from alcohol and hepatitis virus
congestive heart failure
stenosis or ischemia may cause reduced pumping capacity of the heart there is decreased cardiac output and raas system is activated to increase retention leading to fluid overload
effects of cardiac congestion
raised JVP
pulmonary oedema
peripheral oedema
liver congestion tachycardia
hepatomegaly
presentation of hepatic central venous congestion
there is stasis of blood which is poorly oxygenated that is the pericentral hepatocytes
periportal hepatocytes
relatively better oxygenated due to proximity of hepatic arterioles
what is oedema
Accumulation of abnormal amounts of fluid in the extravascular compartment
intercellular tissue compartment (extracellular fluid) body cavities
peripheral oedema
increased interstitial fluid in tissues
what is an exudate
Part of inflammatory process* due to vascular permeability
Tumour, inflammation, allergy
Higher protein/albumin content (cells)
H2O & electrolytes
High specific gravity
pathophysiology of oedema
there is increased hydrostatic pressure which leads to transudate
pathophysiology of peripheral oedema
right side failure , hypertrophy of the right ventricle means high pressure difficult for the return of blood, blood retention in systemic veins .
there is increased blood pressure in capillaries and increased filtration rate
pathophysiology of lymphatic blockage
lymphatic Obstruction – hydrostatic pressure upset
Lymphatic drainage is required for normal flow
If lymphatic system blocked lymphoedema
pathophysiology of oedema in abnormal renal function
Abnormal renal function results in Salt (NaCl) and H2O retention
Secondary in heart failure - reduced renal blood flow
Primary: acute tubular damage eg hypotension
renal function is the result of both
salt and H2O
intravascular fluid volume
secondary PC
oedema
pathophysiology of low protein oedema
due to the insufficient proteins in the body there is decreased oncotic pressure and therefore increased filtration levels
causes of low protein levels
e.g. nephrotic syndrome leaky renal glomerular basement membrane; lose protein; generalised oedema
e.g. hepatic cirrhosis diffuse nodules and fibrosis in liver; liver unable to synthesise enough protein
e.g. malnutrition insufficient intake of protein
LP.S[(PC-Pi)-(C-i)] =JV
pathophysiology of permeability oedema
there is increased endothelial permeability causes exudate.
examples of pathophysiology of permeability oedema
burns
acute inflammation such as pneumonia