(QUIZ) bacteriostatic

Question 1

Tetracyclines (4)
T
D
D
M

Gram (+) & (-)

Answer 1

Tetracycline
Demeclocycline
Doxycycline
Minocycline

Question 2

Tetracycline MOA

broad spectrum

Answer 2

Inhibits tRNA binding to mRNA =inhibits growing peptide chain (protein synthesis)

Question 3

Tetracycline uses

Answer 3

ear infection/URI
Rocky Mountain/typhus/Q fever
Chlamydia
Cholera
Mycoplasma pneumoniae
Lyme disease
Anthrax
H.pylori
Acne

Question 4

Tetracycline AE

Answer 4

Stained/hypoplasia teeth
Photosensitivity 
Superinfection 
Hepatotoxicity (doxy/mino)
Renal toxicity (tetra/Deme)

Question 5

Tetracycline reduced absorption with

Take 1 hr before/2 hrs after

Answer 5

Metal ions-
Ca/iron/mag supps, antacids, milk

Food

Question 6

Macrolides  (inhibit protein synthesis)
C
A
C
E

Answer 6

Clarithromycin
Azithromycin
Clindamycin- c.diff, CAMRSA
Erythromycin -(^1/2 warfarin/carbamazepine/theophylline)

Question 7

Macrolides uses

Answer 7

Anaerobic (+/-) outside CNS 
PNA
MAC
Chlamydia 
H.flu
Whooping cough, diphtheria, group A strep

Question 8

All macrolides cause _______

Answer 8

QT prolongation

Question 9

Avoid ___use w macrolides= Myopathies and ^QT

Answer 9

Avoid statin use w macrolides

simvastatin =^QT

Question 10

Linezolid use reserved for
____/___

Also susceptible
____
____

Answer 10

MRSA/VRE

Also susceptible:
MRSE
Streptococcus pneumoniae (PCN sens/res)

Question 11

Linezolid & Tesizolid AE
(oxazolidinones)
(bacteriostatic, protein synth inhibitor)

Answer 11

Myelosuppression (weekly cbc)

Rare neuropathies

Question 12

Linezolid Interactions

2

Answer 12

MAOI

SSRI

Question 13

Telithromycin
Use:
(ketolide)

Answer 13

Strep pneumoniae

Question 14

Telithromycin SE

4

Answer 14

^QT
Liver injury
Visual
GI

Question 15

Telithromycin BB Warning

Answer 15

Worsening muscle weakness w myasthenia gravis

Question 16

Dalfopristin principle indication
AE:
(inhibits protein synthesis)
(streptogramin)

Answer 16

VRE not responding to vanc

hepatotoxicity

Question 17

Dalfopristin drug interactions

Answer 17

Any metabolized by CYP3A4

Question 18

Chloramphenicol

Use

Answer 18

Only used for life threatening emergencies

Question 19

Chloramphenicol AE

3

Answer 19

Myelosuppression
BBW!!-fatal aplastic anemia
Gray syndrome

Question 20

____ & ____ used for impetigo

Answer 20

Retapamulin & mupirocin

Question 21

Doxycylcine uses

Answer 21

CAMRSA, pna (chllamydia/mycoplasma), RMSF, lyme, acne, anthrax

Question 22

Minocycline use

Answer 22

RA, acne

Question 23

tetracycline

Answer 23

acne, resp infections, skin infection