(QUIZ) Antimicrobials

Question 1

Bacteriostatic

ECSTaTiC

Answer 1

Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracycline 
Chloramphenicol

Question 2

Bactericidal

(Very
Finely
Proficient 
At
Cell
Murder)

Answer 2

Vancomycin
Fluoroquinolones 
Penicillin
Aminoglycosides 
Cephalosporin
Metronidazole

Question 3

Beta Lactam Family 
I
C
A
M
E

Answer 3

Imipenem
Cephalosporins 
Aztreonam
Meropenem
Ertapenem

Question 4

Narrow spectrum Penicillin

Answer 4

Penicillin G

Penicillin V

Question 5

Penicillin G, Penicillin V use

Answer 5

Strep & syphilis

Question 6

Penicillinase resistant (narrow spectrum)
(anti-\_\_\_\_)
O
N
D

Answer 6

Anti-staphylococcal
oxacillin
Nafacillin
Dicloxicin

Question 7

Broad spectrum Penicillin (2)

Use: (3)

Answer 7

Amoxicillin & Ampicillin

Strep, AOM, Lyme <8y/o

Question 8

Broad spectrum Penicillin coverage

Answer 8

Amoxicillin & Ampicillin
Gram +: enterococcus fecalis

Gram -: h.flu, salmonella, shigella, proteus mirabalis

Question 9

Penicillin Extended spectrum
(2)
(anti-pseudomonal)
Coverage:(5)

Answer 9

Piperacillin & Ticarcillin

Pseudomonas, enterobacter, bactericides fragilis, klebsiella, proteus

(NO MRSA)

Question 10

Penicillin alternative

Answer 10

(Macrolides)

Vanc, erythromycin, clindamycin effective

Question 11

Penicillin susceptible organisms: gram (____)

Answer 11

Gram negative

Question 12

Beta lactamase inhibitors

No MRSA coverage**

Answer 12

Clavulanic acid
Tazobactam (/piperacilin for pseudomonas)
Sublactam

Question 13

Cephalosporins are ___-___ resistant

Similar ____structure

Answer 13

Beta-lactam resistant

Similar to Penicillin structure (cross allergy)

Question 14

1st gen cephalosporins
(3)

Use:

Answer 14

Cefazolin
Cephalexin
Cefadroxil

Use: Gram +, pre-surgical prophylaxis

Question 15

2nd gen Cephalosporins

Gives beta lactamase coverage but Not pseudomonas or meningitis

Answer 15

Cefoxitin (anaerobic bacterioides)
Cefaclor
Cefotetan
cefprozil
Cefuroxime (URI: h.flu, pneumococci, staphylococci)
Cefmetazole
cefonicid
Loracarbef

Question 16

Vancomycin (narrow) bind to ___ of cell wall synthesis

No interaction w PBPs

Answer 16

Precursors

Question 17

Vancomycin uses
Gram (\_\_)
\_\_\_/\_\_\_
S\_\_\_\_\_\_
P\_\_\_\_ \_\_\_ \_\_\_\_
C\_\_\_\_

Answer 17

Gram positive
MRSA/MRSE
Streptococci
PCN resistant pneumococci
Cdiff

Question 18

Vancomycin  AE
\_\_\_toxicity
R\_\_\_\_
T\_\_\_
T\_\_\_\_\_
\_\_\_\_\_\_failure r/t dosage

Answer 18

Ototoxicity 
Redman
Thrombophlebitis 
Thrombocytopenia
Renal failure

Question 19

What meds increases risk of renal failure with vancomycin
A
C
N

Answer 19

Aminoglycosides
Cyclosporine
NSAIDS

Question 20

3rd Generation Cephalosporin

Answer 20

cefotaxime
cefdinir
cefditorin
cefixime
cefpodoxime
ceftazdime
cefibuten
ceftriaxone
cefoperazone
ceftizoxime

Question 21

3rd generation coverage Cephalosporin

Answer 21

can enter spinal fluid , gram negative,

NO pseudomonas or enterococcus

Question 22

4 Generation Cephalosporin

Answer 22

cefepime
ceftolozane
usually given w tazobactam to ^spectrum
covers pseudomonas and hosp acq. infections

Question 23

5th gen cephalosporins

Answer 23

ceftaroline
covers: MRSA, VRSA, CAP,
ceftolozaone broad spectrum gram +/-
pseudomonas & some enterobacter

Question 24

cephalosporin alcohol rxcn

Answer 24

cephazolin
cefmetazole
cefoperazone
cefotetan

Question 25

Cephalosporin bleeding rxcn

vProthrombin thru vit K interference

Answer 25

cefotetan
ceftriaxone
cefmetazole
cefoperazone

Question 26

Carbapenem (5)

Answer 26

imipenem- given w vanc
meropenem-meningitis
ertapenem- for: acute pelvic infections, GI/GU, soft tissue infection, CAP; NOT pseudomonas
doripenem-intra abd. inf/uti
avibactam-w ceftazidime for intra abd/uti

Question 27

Carbapenems cover
excreted thru __
lower levels of __

Answer 27

gram -/+
excreted through kidneys
lower valproate