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Path IV Quizzes > Quiz 4 Joint > Flashcards

Quiz 4 Joint Flashcards

1
Q

Most common joint pathology

A

osteoarthritis

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2
Q

x-ray findings osteoarthritis

A

joint space narrowing
sclerosis
osteophyte
subchondral bone cysts

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3
Q

Where are haberdon nodes in osteoarthritis?

A

DIPS

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4
Q

RA spares what?

A

DIPS

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5
Q

Antibodies found in RA?

A

anti-cintrullinated protein antibodies (anti-CCP)

RF

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6
Q

hist of RA

A

increased lymphocytes and

proliferated synoviocytes

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7
Q

RA on x-ray

A 
subluxation deformities
(incomplete separation)
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8
Q

triad of RA with splenomegaly and hypersplenism

A

Felty’s syndrome

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9
Q

What do you call RA under 16?

A

JRA or JIA or Still’s disease

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10
Q

What are the 4 types of seronegative spondyloarthropathies that are seronegative for RF and are characterized by inflammatory arthritis in occurrence with other conditions?

A

ankylosing spondylitis (AS)
reactive arthritis
psoriatic arthritis (PA)
enteropathic arthritis

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11
Q

all of the seronegatives are associated with what gene locus?

A

HLA-B27

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12
Q

What does AS affect?

A

axial skeleton, especially SI joints

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13
Q

bamboo sign on x-ray

A

AS

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14
Q

cause of reactive arthritis

A

past infection causes immune reaction that cross reacts (?)

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15
Q

1 most common organism to cause reactive arthritis associated with GU infection?

A

chlamydia

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16
Q

What GI infections can cause reactive arthritis?

A

Shigella
Salmonella
yersinia
Campylobacter

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17
Q

triad in reactive arthritis

A

urethritis
cervicitis
conjunctivitis

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18
Q

most common infections leading to reactive arthritis

A

GI in origin

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19
Q

synovitis/sausage toe

A

seen in reactive arthritis

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20
Q

lesions on palms and feet (keratosomething)

A

reactive arthritis

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21
Q

non-reactive arthritis associated with IBD and following a bowel infxn of salmonella, shigella, yersinia, or campylobacter

A

enteropathic arthritis

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22
Q

psoriatic arthritis affects what?

A

DIPS

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23
Q

pitting and onycholysis of nails is seen in?

A

psoriatic arthritis

24
Q

1 and #2 bugs to cause septic arthritis

A

staph

strep

25
Q

what causes septic spinal arthritis and what is it called?

A

TB can cause

called Potts

26
Q

Lyme arthritis caused by what and what is vector?

A

borrelia burgdorferi

27
Q

most common cause of bacterial or supperative arthritis in adults and older children

A 
#1 Staph
#2 strep
28
Q

most common cause of bacterial arthritis in elderly, IV drug users, and the seriously ill?

A

e. coli

29
Q

In cases of non-gonococcal arthritis is it common for single or multiple joints to be involved

A

non-gonoccocal: single

gonococcal: multiple

30
Q

how is TB arthritis spread to the joint?

A

spread to joint via adjacent TB osteomyelitis or hematogenous spread of pulmonary TB

31
Q

what does TB arthritis affect?

A

hips, knees, ankles (weight bearing joints)

32
Q

What is TB of the spine?

A

Pott’s disease

affects T and L spine

33
Q

lyme arthritis caused by what?

A

spirochete: borrelia burgdorferi

34
Q

lyme involved joints

A

knees, ankles, shoulders, elbows

35
Q

lyme vector

A

deer tick (ixodes)

36
Q

what type of stain shows spirochetes?

A

silver stain

37
Q

What viruses can cause viral arthritis?

A

Hep B and C, HIV, Parvo B19, rubella

38
Q

gout vs pseudogout

A

gout: monosodium urate crystals
pseudogout: calcium pyrophosphate crystals

39
Q

what can develop as a result of increased uric acid production or decreased uric acid excretion?

A

hyperuricemia

40
Q

what drugs should you not take with gout?

A

aspirin, thiazide diuretics, loop diuretics

41
Q

saturnine gout?

A

from moonshine with lead

42
Q

what is pathognomonic for gout?

A

tophus

43
Q

Is gout or pseudogout birefringent?

A

both

44
Q

histology of gout

A

needle like crystals surrounded by inflammatory and giant multinucleated cells

45
Q

hist of pseudogout

A

rhomboidal, intracellular crystal

46
Q

ganglionic cysts

A

lack true cell lining

fluid doesn’t communicate with joint space

47
Q

synovial cyst

A
  • fluid does communicate with joint space
  • herniation of synovial fluid through joint tissue
  • also called bakers cyst
48
Q

Bakers/Synovial cysts can be a complication of what?

A

RA

49
Q

several, closely related, benign neoplasms that can develop in synovial linings of joints, tendon sheets, and bursae

A

villonodular synovitis

50
Q

most common types of villonodular synovitis

A

pigmented villonodular synovitis (PVNS) and diffuse-type giant cel tumor of tendon sheet (GCTTS)

51
Q

what makes villonodular synovitis stain pink?

A

hemosiderin

52
Q

malignant synovioma

A

synovial sarcoma

knee, ankle in young adults

53
Q

What antigens is RA associated with?

A

Class II antigens such as HLA-DR4

54
Q

In what population is N gonorrhoea most commonly seen in bacterial arthritis?

A

young adults

55
Q

where do you see keratoderma blenorrhagica?

A

characteristic rash of reactive arthritis

Path IV Quizzes (18 decks)

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