Quiz 4 Joint

Question 1

Most common joint pathology

Answer 1

osteoarthritis

Question 2

x-ray findings osteoarthritis

Answer 2

joint space narrowing
sclerosis
osteophyte
subchondral bone cysts

Question 3

Where are haberdon nodes in osteoarthritis?

Answer 3

DIPS

Question 4

RA spares what?

Answer 4

DIPS

Question 5

Antibodies found in RA?

Answer 5

anti-cintrullinated protein antibodies (anti-CCP)

RF

Question 6

hist of RA

Answer 6

increased lymphocytes and

proliferated synoviocytes

Question 7

RA on x-ray

Answer 7

subluxation deformities
(incomplete separation)

Question 8

triad of RA with splenomegaly and hypersplenism

Answer 8

Felty’s syndrome

Question 9

What do you call RA under 16?

Answer 9

JRA or JIA or Still’s disease

Question 10

What are the 4 types of seronegative spondyloarthropathies that are seronegative for RF and are characterized by inflammatory arthritis in occurrence with other conditions?

Answer 10

ankylosing spondylitis (AS)
reactive arthritis
psoriatic arthritis (PA)
enteropathic arthritis

Question 11

all of the seronegatives are associated with what gene locus?

Answer 11

HLA-B27

Question 12

What does AS affect?

Answer 12

axial skeleton, especially SI joints

Question 13

bamboo sign on x-ray

Answer 13

AS

Question 14

cause of reactive arthritis

Answer 14

past infection causes immune reaction that cross reacts (?)

Question 15

1 most common organism to cause reactive arthritis associated with GU infection?

Answer 15

chlamydia

Question 16

What GI infections can cause reactive arthritis?

Answer 16

Shigella
Salmonella
yersinia
Campylobacter

Question 17

triad in reactive arthritis

Answer 17

urethritis
cervicitis
conjunctivitis

Question 18

most common infections leading to reactive arthritis

Answer 18

GI in origin

Question 19

synovitis/sausage toe

Answer 19

seen in reactive arthritis

Question 20

lesions on palms and feet (keratosomething)

Answer 20

reactive arthritis

Question 21

non-reactive arthritis associated with IBD and following a bowel infxn of salmonella, shigella, yersinia, or campylobacter

Answer 21

enteropathic arthritis

Question 22

psoriatic arthritis affects what?

Answer 22

DIPS

Question 23

pitting and onycholysis of nails is seen in?

Answer 23

psoriatic arthritis

Question 24

1 and #2 bugs to cause septic arthritis

Answer 24

staph

strep

Question 25

what causes septic spinal arthritis and what is it called?

Answer 25

TB can cause | called Potts

Question 26

Lyme arthritis caused by what and what is vector?

Answer 26

borrelia burgdorferi

Question 27

most common cause of bacterial or supperative arthritis in adults and older children

Answer 27

``` #1 Staph #2 strep ```

Question 28

most common cause of bacterial arthritis in elderly, IV drug users, and the seriously ill?

Answer 28

e. coli

Question 29

In cases of non-gonococcal arthritis is it common for single or multiple joints to be involved

Answer 29

non-gonoccocal: single | gonococcal: multiple

Question 30

how is TB arthritis spread to the joint?

Answer 30

spread to joint via adjacent TB osteomyelitis or hematogenous spread of pulmonary TB

Question 31

what does TB arthritis affect?

Answer 31

hips, knees, ankles (weight bearing joints)

Question 32

What is TB of the spine?

Answer 32

Pott's disease | affects T and L spine

Question 33

lyme arthritis caused by what?

Answer 33

spirochete: borrelia burgdorferi

Question 34

lyme involved joints

Answer 34

knees, ankles, shoulders, elbows

Question 35

lyme vector

Answer 35

deer tick (ixodes)

Question 36

what type of stain shows spirochetes?

Answer 36

silver stain

Question 37

What viruses can cause viral arthritis?

Answer 37

Hep B and C, HIV, Parvo B19, rubella

Question 38

gout vs pseudogout

Answer 38

gout: monosodium urate crystals pseudogout: calcium pyrophosphate crystals

Question 39

what can develop as a result of increased uric acid production or decreased uric acid excretion?

Answer 39

hyperuricemia

Question 40

what drugs should you not take with gout?

Answer 40

aspirin, thiazide diuretics, loop diuretics

Question 41

saturnine gout?

Answer 41

from moonshine with lead

Question 42

what is pathognomonic for gout?

Answer 42

tophus

Question 43

Is gout or pseudogout birefringent?

Answer 43

both

Question 44

histology of gout

Answer 44

needle like crystals surrounded by inflammatory and giant multinucleated cells

Question 45

hist of pseudogout

Answer 45

rhomboidal, intracellular crystal

Question 46

ganglionic cysts

Answer 46

lack true cell lining | fluid doesn't communicate with joint space

Question 47

synovial cyst

Answer 47

- fluid does communicate with joint space - herniation of synovial fluid through joint tissue - also called bakers cyst

Question 48

Bakers/Synovial cysts can be a complication of what?

Answer 48

RA

Question 49

several, closely related, benign neoplasms that can develop in synovial linings of joints, tendon sheets, and bursae

Answer 49

villonodular synovitis

Question 50

most common types of villonodular synovitis

Answer 50

pigmented villonodular synovitis (PVNS) and diffuse-type giant cel tumor of tendon sheet (GCTTS)

Question 51

what makes villonodular synovitis stain pink?

Answer 51

hemosiderin

Question 52

malignant synovioma

Answer 52

synovial sarcoma | knee, ankle in young adults

Question 53

What antigens is RA associated with?

Answer 53

Class II antigens such as HLA-DR4

Question 54

In what population is N gonorrhoea most commonly seen in bacterial arthritis?

Answer 54

young adults

Question 55

where do you see keratoderma blenorrhagica?

Answer 55

characteristic rash of reactive arthritis