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Path IV Quizzes > Quiz 1 Female > Flashcards

Quiz 1 Female Flashcards

1
Q

hist of psoriasis of vulva

A 
elongation/increased depth of rete ridges
hyperkeratosis
parakeratosis
loss of granular layer
vascular dilation
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2
Q

What are the 3 aspects of psoriasis?

A

1) Kebners phenomenon: lesions that occur after trauma.
2) Asuspitz sign
3) Blanching around lesions in skin

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3
Q

Lichen simplex chronicus

A

scratch itch scratch cycle

thickened epithelium

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4
Q

hist of lichen planus

A

saw tooth rete ridges

leukocytes

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5
Q

Lichen sclerosis

A
  • thickening of skin of vulva and peri-anal area

- appears pale/white

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6
Q

What % of pt with lichen sclerosis will develop cancer?

A

5%

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7
Q

hist of lichen sclerosis?

A
  • rete ridges disappear
  • atrophy
  • lymphocytes
  • edematous degeneration of basal layer
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8
Q

hist of lichen simplex chronicus

A

thickening of rete ridges
thickened epithelium
hyperkeratosis

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9
Q

what virus causes moloscum contagiousum?

A

pox virus

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10
Q

how do you distinguish lesions of moloscum contagiousum?

A

umbilicated

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11
Q

If lesions of many conditions look the same, how do you distinguish?

A

Biopsy to look at rete ridges

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12
Q

1 bacteria to cause bartholins duct cysts?

A

e. coli

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13
Q

hist of HSV 2?

A

multinucleate giant cell

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14
Q

what strains of HPV cause genital warts?

A

6 and 11

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15
Q

what strains of HPV cause CA?

A

16 and 18 (31 and 45 less common)

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16
Q

what do you call a genital wart?

A

condyloma acuminata

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17
Q

does a bartholin cysts = STI?

A

no

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18
Q

what is actual name of syphilis?

A

treponema pallidum

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19
Q

what is a painless ulcer? what causes it?

A 
chancre
syphilis (treponema pallidum)
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20
Q

his of syphilis

A

gm -

spirochete

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21
Q

what is a flat wart? what causes it?

A

condyloma latum

syphilis

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22
Q

hist of condyloma acuminata

A

acanthosis
hyperkeratosis
cytoplasmic vacuolation

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23
Q

discharge of BV

A

thick, creamy, noxious smell (fishy)

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24
Q

discharge of trichomonas

A

foamy, noxious smell

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25
candida discharge
non-noxious smell
26
most common vaginal infection? what causes it?
BV | gardeneralla and bacteroides
27
what is second most common vaginal infection?
candida
28
criteria to dx BV?
- fishy oder - increased pH - sticky, thick, white d/c - clue cells (appear shimmering)
29
gonorrhoeae
gm - diplococci looks like 2 kidney beans extracellular and intracellular
30
chlamydia trachomatis
intracellular infected cells look pink red, friable cervix
31
third most common vaginal infection
trichomonas: flagellated protazoa
32
vulvar intraepithelial neoplasia (VIN)
significant variety of colored plaques (hyper pigmentation)
33
hist of VIN
basiloid and warty cells | or well differentiated cells
34
if warty and basiloid cells of VIN, what is it associated with?
HPV 16 and 18
35
which form of cells indicates more aggressive VIN?
well-differentiated | not associated with HPV
36
most common vulvar CA
SCC
37
most common vulvar CA
SCC
38
what is adenocarcinoma of vagina linked to?what is it called?
mother who was treated with DES | clear cell adenocarcinoma
39
hist of clear cell adenocarcinoma
vacuolated tumor cells in clusters gland like structures nuclei look clear
40
risks for cervical ca
``` early age of first intercourse multiple sexual partners persistent infection of high risk HPV presence of cancer associated HPV strains exposure to oral contraceptives tobacco use history of chlamydia or others multiple births ```
41
koilocytosis
large nuclei that stain dark with halo HPV associated ASC-US or atypical squamous cells
42
endometriosis
endometrial tissue outside uteran cavity
43
where is #1 location for endometriosis?
ovaries
44
what cause infertility in endometrial pt
scar formation, adhesions, anatomical distortions of involved ovary, fallopian tubes, or uterus inflammation
45
endometrioma
chocolate cyst | ovarian cyst from ectopic endometrial tissue that bleeds within ovary
46
adenomyosis
endometrial tissue in muscle wall of myometrium of uterus
47
endometritis
infection or inflammation of endometrium | caused by retaining pieces of placenta or infections or PID
48
acute endometritis
micro-abscesses or neutrophils within endometrial glands | most are poly-microbial
49
chronic endometritis
``` presence of plasma cells in stroma doesn't respond to antibiotics eccentric nucleus (off to one side) ```
50
most common location of PID
ovaduct/fallopian tube
51
sequelae of PID
scarring of fallopian tube rate of ectopic pregnancy increases 6-10 fold tubo-ovarian abscess salpingo-oophoritis with tubo-ovarian abscess
52
Atypical hyperplasia
estrogen dominant state | persistent hyperplasia has high likelihood of becoming malignant
53
Most common gynocologic cancer in US
endometrial ca
54
most common type of endometrial ca? who gets it?
adenocarcinoma | post-menopausal women
55
risk factors for endometrial ca
``` nulliparity obesity hyperglycemia DM HTN ```
56
most common type of endometrial cancer
adenocarcinoma
57
leiomyoma
fibroid benign smooth muscle tumor of uterus whorled pattern of smooth muscle
58
malignant leiomyoma and hist
``` leiomyosarcoma hyperchromatic deeply staining nuclei more pleomorphism irregular nucleus ```
59
most common endocrine disorder in females and cause
PCOS | - caused by excessive androgenic hormones like testosterone which is stimulated by excess LH from ant pit
60
PCOS on imaging looks like?
string of pearls
61
PCOS related to?
DM insulin resistance hyperglycemia obesity
62
serous cyst adenoma
benign epithelial tumors of ovary that can become very big | single celled lining like fallopian tube
63
mucinous cyst adenoma
single cell layer of mucin | similar to endocervix
64
ovarian ca
psammoma body: small calcification stains pink/purple staining - also found in other conditions
65
ovarian serous cystadenocarcinoma is characterized by what?
psammoma body: small rounded, purple staining calcification | - also found in other conditions
66
what is the difference between acute and chronic endometritis?
acute: micro-abscesses or neutrophils within endometrial glands chronic: plasma cells in stroma - doesn't respond to antibiotics
67
what is the difference between acute and chronic endometritis?
acute: micro-abscesses or neutrophils within endometrial glands - polymycrobial chronic: plasma cells in stroma - doesn't respond to antibiotics
68
what infection is most commonly linked with chronic endometritis?
PID
69
20% of endometrial cancers which type? Notable for what?
- papillary serous carcinoma | - accumulation of p53 protein

Path IV Quizzes (18 decks)

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