Quiz 3 Parathyroid Flashcards
light to dark pink, eosinophilic, polygonal, central, round nucleus contains secretory granules
chief cells
what do chief cells located in parathyroid gland secrete?
PTH
what type of cells are few in number, smaller nuclei.
oxyphil cells (don’t know what they secrete)
What hormone decreases serum calcium?
calcitonin
what cells secrete calcitonin?
parafollicular cells of thyroid gland
PTH1 receptors are where?
bone and kidney
PTH effects kidneys how?
increases renal tubular Ca reabsorption and phosphate excretion
converts vit D to active form
how does PTH effect bone?
increase Ca and phosphate reabsorption in intestine Ca
Ca>PO4
how does vit D effect Ca?
increases serum Ca and PO4 reabsorption in intestine
Ca>PO4
1 cause of primary hyperparathyroid outpatient and overall
parathyroid adenoma
1 cause of primary hyperparthyroid inpatient?
parathyroid carcinoma
single mass in parathyroid gland, identical appearing cell population, no adipose tissue, no mitotic figures
parathyroid adenoma
1 cause of secondary hyperparathyroid
renal failure
reduced adipose tissue in parathyroid gland, but all cell types still present
primary hyperplasia (seen in secondary hyperparthyroid due to renal failure)
abrupt onset of hypercalcemic related symptoms (bone pain, renal stones)
parathyorid carcinoma
