Quiz 3 Pancreas

Question 1

light staining spherical clusters that produce hormones

Answer 1

islet of Langerhans

Question 2

alpha cells secrete

Answer 2

glucagon

Question 3

beta cells secrete

Answer 3

insulin and amylin

Question 4

delta cells secrete

Answer 4

somatostatin

Question 5

enterochromaffin cells secrete

Answer 5

serotonin

Question 6

insulin effects on islet cells

Answer 6

activates beta cells and inhibits alpha cells

Question 7

glucagon effects on islet cells

Answer 7

activates alpha cells and then alpha cells activate delta cells

Question 8

somatostatin effect on islet cells

Answer 8

inhibits alpha and beta cells

Question 9

1 type of primary DM

Answer 9

DM2 (85-95%)

Question 10

2 type of DM

Answer 10

DM1 (5-10%)

Question 11

3 type of DM

Answer 11

DM1.5 (5%)

Question 12

Autoimmune disease with islet destruction by immune cells reacting to endogenous b-cell antigens

Answer 12

Type 1 DM

Question 13

antibodies to DM1

Answer 13

anti-islet cell Ab

anti-insulin Ab

Question 14

Presence of lymphocytic infiltrates in the islets of Langerhan suggests what?

Answer 14

suggests autoimmune mechanism (DM1)

Question 15

Insulin resistance and decreased production of insulin by B cells

Answer 15

DM2

Question 16

Pink hyalinization and amyloid deposition in the islets of langerhans

Answer 16

DM2

Question 17

1 cause of vision loss due to retinopathy

Answer 17

diabetic retinopathy

Question 18

dilated capillaries, micro aneurism lead to leaked RBC leads to retinal hemorrhage, edema, exudate

Answer 18

non-proliferative diabetic retinopathy

Question 19

lack of oxygen to retina leads to development of fragile new blood vessels that lead to retinal detachment

Answer 19

proliferative diabetic retinopathy

Question 20

earliest detectable change is thickening of capillaries within glomeruls, then nodular glomerulosclerosis

Answer 20

diabetic retinopathy

Question 21

pacreatic tumor derived from beta cells that secretes gastrin and leads to excess HCL and ulcerations

Answer 21

gastrinoma

Question 22

1 location of gastrinoma

Answer 22

duodenum

Question 23

triad of gastric acid hyper secretion, severe peptic ulceration, and gastrinomas of pancreas or duodenum

Answer 23

Zollinger-Ellison Syndrome