Quiz 3 Thyroid Flashcards
what cells secrete calcitonin?
c-cells in colloid of thyroid
TSH level in hypothyroid?
increased
1 cause of hypothyroid in US?
Hashimoto’s
1 cause of hypothyroid worldwide?
iodine deficiency
High TSH, low T3/T4
hypothyroid
1 cause of hyperthyroid in US and WW?
Graves
2 cause of hyperthyroid?
pituitary dysfunction
What are the antibodies in epithelial cells in Hoshimoto’s?
anti-microsomal ab and anti- TPO ab
What are the antibodies in colloid of Hoshimotos?
anti-thyroglobulin ab
lymphocytic infiltration and fibrosis, no tissue hypertrophy, lymphocytes aggregate around colloid, and may see Hurthle cells?
hashimotos
Why do you need iodine for thyroid function?
To produce thyroxine
enlarged epithelial cells that stain pink with abundant eosinophilic granular cytoplasm due to altered mitochondria?
Hurthle cell
Where do you see Hurthle cells?
Hashimoto’s, follicular thyroid CA
Granulomas and multinucleate giant cells in colloid of thyroid?
DeQuervain’s Subacute Thyroiditis
1 congenital neck malformation
thyroglassal duct cyst
1 location of thyroglossal duct cyst
between isthmus and hyoid bone
1 thyroid ca
papillary carcinoma
follicles irregularly enlarged and surrounded by flattened epithelium, associated with lack of increased thyroid activity
non-toxic multinodular goiter
marked hypercellularity consistent with hyper functioning thyroid
toxic nodular goiter/toxic thyroid nodule
What ab are present in Graves disease?
anti-LATS ab
hyper plastic epithelium, prominent scalloped colloid, tall columnar epithelium
Grave’s
cold nodules on thyroid scan?
colloid cysts
well encapsulated, like normal tissue, follicles containing colloid with variability in size
follicular adenoma
are the majority of thyroid cancers malignant and unresponsive to therapy?
No, majority are benign and responsive to treatment
