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Path IV Quizzes > Quiz 3 Thyroid > Flashcards

Quiz 3 Thyroid Flashcards

1
Q

what cells secrete calcitonin?

A

c-cells in colloid of thyroid

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2
Q

TSH level in hypothyroid?

A

increased

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3
Q

1 cause of hypothyroid in US?

A

Hashimoto’s

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4
Q

1 cause of hypothyroid worldwide?

A

iodine deficiency

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5
Q

High TSH, low T3/T4

A

hypothyroid

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6
Q

1 cause of hyperthyroid in US and WW?

A

Graves

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7
Q

2 cause of hyperthyroid?

A

pituitary dysfunction

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8
Q

What are the antibodies in epithelial cells in Hoshimoto’s?

A

anti-microsomal ab and anti- TPO ab

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9
Q

What are the antibodies in colloid of Hoshimotos?

A

anti-thyroglobulin ab

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10
Q

lymphocytic infiltration and fibrosis, no tissue hypertrophy, lymphocytes aggregate around colloid, and may see Hurthle cells?

A

hashimotos

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11
Q

Why do you need iodine for thyroid function?

A

To produce thyroxine

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12
Q

enlarged epithelial cells that stain pink with abundant eosinophilic granular cytoplasm due to altered mitochondria?

A

Hurthle cell

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13
Q

Where do you see Hurthle cells?

A

Hashimoto’s, follicular thyroid CA

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14
Q

Granulomas and multinucleate giant cells in colloid of thyroid?

A

DeQuervain’s Subacute Thyroiditis

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15
Q

1 congenital neck malformation

A

thyroglassal duct cyst

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16
Q

1 location of thyroglossal duct cyst

A

between isthmus and hyoid bone

17
Q

1 thyroid ca

A

papillary carcinoma

18
Q

follicles irregularly enlarged and surrounded by flattened epithelium, associated with lack of increased thyroid activity

A

non-toxic multinodular goiter

19
Q

marked hypercellularity consistent with hyper functioning thyroid

A

toxic nodular goiter/toxic thyroid nodule

20
Q

What ab are present in Graves disease?

A

anti-LATS ab

21
Q

hyper plastic epithelium, prominent scalloped colloid, tall columnar epithelium

A

Grave’s

22
Q

cold nodules on thyroid scan?

A

colloid cysts

23
Q

well encapsulated, like normal tissue, follicles containing colloid with variability in size

A

follicular adenoma

24
Q

are the majority of thyroid cancers malignant and unresponsive to therapy?

A

No, majority are benign and responsive to treatment

25
Q

risk factors for papillary carcinoma?

A

female
hx of neck irradiation
young

26
Q

prognosis for papillary carcinoma of thyroid is worse in what population?

A

elderly

27
Q

frondlike tissue with fibrovascular core?

A

papillary carcinoma

28
Q

what other tumors contain psamomma bodies?

A

ovarian papillary cystadenocarcinoma

prolactinoma

29
Q

proliferation of parafollicular cells and lots of calcitonin in serum, pink hyaline material that looks like amyloid

A

medullary carcinoma

30
Q

most malignant thyroid cancer?

A

undifferentiated/anaplastic

Path IV Quizzes (18 decks)

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