Quiz 11 - Blood Flashcards

1
Q

composition and functions of blood

A

blood acts as transport medium to distribute substances to and from body tissues

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2
Q

basis functions of blood

A

distribution
regulation
protection

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3
Q

distribution by blood

A

transports:

  • O2 from lungs and nutrients from GI tract to cells
  • metabolic wastes from cells to lungs and kidneys for elimination
  • hormones from endocrine glands to target organs
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4
Q

regulation by blood

A

maintains:

  • body temperature by absorbing and distributing heat
  • pH in body tissues using buffer systems
  • fluid volume in circulatory system
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5
Q

protection by blood

A

prevents:

  • blood loss by initiating clot formation when a vessel is broken
  • infections by synthesizing and utilizing antibodies and white blood cells against pathogens
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6
Q

components of blood

A

plasma plus formed elements and hematocrit (Hct)

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7
Q

hematocrit

A

% of RBCs in centrifuged blood sample

- when centrifuged, blood separates into heavier formed elements on bottom and lighter plasma on top

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8
Q

average Hct for men and women

A

men ~46%

women ~ 42%

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9
Q

physical characteristics of blood

A
  • more dense than water (viscous)
  • alkaline pH = 7.4
  • temp = 38C
  • accounts for ~7% of body weight
  • avg volume: males ~5L, women ~4L
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10
Q

components of plasma

A
water (90% of plasma)
plasma proteins (8%)
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11
Q

types of plasma proteins

A

albumin
fibrinogen
globulins

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12
Q

albumin

A

regulates osmotic pressure (water balance)

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13
Q

fibrinogen

A

clotting proteins

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14
Q

globulins

A

transport lipids and antibodies

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15
Q

substances transported by blood

A

respiratory gasses
nutrients
hormones
electrolytes

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16
Q

formed elements

A

erythrocytes
leukocytes
platelets

17
Q

structure of erythrocytes

A
  • biconcave shape (increases surface area, stackable, flexible)
  • no nucleus (unable to divide, grow, or synthesize proteins)
  • > 97% hemoglobins
  • no mitochondria (ATP is generated anaerobically)
18
Q

function of erythrocytes

A

carry O2 from lungs to tissue and carry CO2 from tissues to lungs

19
Q

hemoglobin

A

major protein of RBCs that carries oxygen

  • reg pigment: oxygenated (red), deoxygenated (dark red)
  • 4 heme molecules: each with an iron that can bind one oxygen
20
Q

erythropoietin

A

hormone released by kidneys which stimulates red blood cell production

21
Q

release of erythropoietin is triggered by…

A
  • hypoxia due to decreased RBCs
  • decreases in oxygen availability
  • increase tissue demand for oxygen
22
Q

fate and destruction of erythrocytes

A
  • life span of a RBC = 100-120 days
  • dying and damaging RBCs are engulfed by macrophages in spleen or liver
  • heme and global are separated and the iron recycled
23
Q

leukocytes

A
  • important in body’s defense against foreign invaders
  • less numerous than RBCs
  • make up 1% of total blood volume
24
Q

types of leukocytes

A
neutrophils
eosinophil
basophil
lymphocyte
monocyte
25
Q

neutrophils

A
  • multi-lobed nuclei
  • most abundant of WBCs
  • phagocytize bacteria
  • 1st of the WBCs to arrive at injury site during inflammation
26
Q

eosinophil

A
  • bi-lobed nuclei
  • 1-4% of WBCs
  • release enzymes that digest large parasites
  • lessen severity of allergies
27
Q

basophil

A
  • most rare of WBCs

-

28
Q

lymphocyte

A
  • > 25% of WBCs
  • primary cells of lymphatic system found mostly in lymphoid tissues (some circulate in blood)
  • become B and T cells, important in immune system
29
Q

monocyte

A
  • 4-*% of WBCs
  • largest of leukocytes
  • arrive at injury site shortly after neutrophils, entering tissue and become macrophages
30
Q

platelets

A

cell fragments

  • structure: small fragments broken off from megakaryocytic in bone marrow
  • function: forms platelet plug that seals injured blood vessel wall