Quiz 10 - Endocrine Flashcards

1
Q

overview of endocrine system

A

endocrine and nervous system cooperate together to maintain homeostasis
nervous - fast acting; specific
endocrine - slower, longer lasting effects

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2
Q

endocrine

A
  • secretes hormone into the bloodstream
  • no ducts
  • glands are highly vascularized (great blood supply)
  • secretions are hormones
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3
Q

exocrine

A
  • secretes onto body epithelial surface
  • secretions travel via ducts onto target organs
  • secretions are usually fluids, lubricants and enzymes
  • examples: sweat, sebum, saliva
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4
Q

endocrine cells

A

grandular secretory cells that release hormones

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5
Q

hormones

A

organized into four groups based on chemical structure:

  • amino acid derivatives
  • eicosanoids
  • peptide hormones
  • steroid hormones
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6
Q

peptide hormones

A
  • amino acid chains (proteins)
  • most hormones are peptides
  • act much like a neurotransmitter receptor
  • acts at the surface of the cell (on receptors)
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7
Q

steroid hormones

A
  • cholesterol based (lipids)
  • easily cross a cell membrane
  • longer lasting effect
  • act inside the cell
  • activates or inhibits specific genes in nuclear DNA
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8
Q

3 mechanisms of Hypothalamus

A
  • act as an endocrine organ itself by releasing hormones via posterior pituitary
  • secretes regulatory hormones that control endocrine cells in anterior pituitary
  • exerts direct neural control over adrenal gland
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9
Q

pituitary gland

A

located below hypothalamus, hangs off of infundibulum

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10
Q

posterior pituitary

A

controlled by nerves from hypothalamus

- produces ADH and oxytocin

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11
Q

target and effect of ADH

A

target - kidneys

effect - decreases urine secretion, vasoconstriction of blood vessels

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12
Q

target and effect of oxytocin

A

target - uterus; mammary glands

effect - lactation; labor contractions

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13
Q

anterior pituitary (function, secretion, target)

A
  • controlled by the hypothalamus: regulates other endocrine glands
  • secretion: hormones that regulate the growth and secretion
  • target: other glands and numerous body tissues
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14
Q

7 hormones produces by anterior pituitary

A
  • ACTH
  • GH
  • TSH
  • prolactin
  • FSH
  • LH
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15
Q

ACTH

A

adrenocorticotropic hormone

activates adrenal cortex to produce glucocoricoids

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16
Q

GH

A

growth hormone

stimulates cell growth and replication (bone & muscle)

17
Q

TSH

A

thyroid-stimulating hormone

targets thyroid gland

18
Q

prolactin

A

stimulates and regulates breast tissue growth and milk production

19
Q

gonadotropins

A

regulates sex organ activities

20
Q

FSH

A

follicle-stimulating hormone

  • promote oocyte development (via estrogen) in women
  • stimulates sperm production in testes
21
Q

LH

A

leutenizing hormone

  • induces ovulation (via progesterone) in women
  • stimulates androgens (testosterone) in men
22
Q

thyroid gland

A

location/structure: anterior surface of trachea, largest purely endocrine gland in the body
produce/secrete: thyroid hormones (thyroxine and triiodothyronine) and C Cell hormone (calcitonin)

23
Q

target and effect of thyroid hormones

A

target: almost all tissues of the body
effect: increase basal metabolic rate, increase O2 consumption, increase heat production, increase protein synthesis

24
Q

target and effect of calcitonin

A

target: bone and kidney
effect: calcium retention

25
Q

parathyroid gland (location, secretion, target, effect)

A

location - 4 pea-sized glands on posterior surface of thyroid, important for Ca homeostasis in human
secretion - parathyroid hormone (PTH)
target - bone, GI tract and kidneys
effect - increase Ca released into blood stream (bone), increase Ca absorption (GI), decreases Ca excretion in urine (kidney)

26
Q

thymus gland (l, s, t, e)

A

location - posterior to sternum, rests on pericardial cavity
secretion - thymosin
target - lymphoid tissue
effect - increased lymphocyte production (immune system)

27
Q

adrenal glands

A

location - attached to both kidneys

  • outer = adrenal cortex
  • inner = adrenal medulla
28
Q

adrenal cortex

A

location - outermost layer (yellow due to lipids), produces more than 24 hormones called adrenocortical steroids, controlled by ACTH from the anterior pituitary

29
Q

secretions of adrenal cortex

A

glomerulosa, fasciculata, reticularis

30
Q

secretion, target and effect of glomerulosa

A

secretion - aldosterone
target - kidneys
effects - increase Na retention

31
Q

secretion, target and effect of fasciculata

A

secretion - cortisol
target - liver and muscles
effects - increase glucose synthesis, increase glycogen formation

32
Q

secretion, target and effect of reticularis

A

secretion - androgens
target - sex organs
effects - pubic hair development in adolescence, promote muscle mass and supports libido in women

33
Q

location, secretion and effect of adrenal medulla

A

location - reddish-brown, due to high vascularity; controlled by SNS
secretion - epinephrine and norepinephrine
effect - increased cardiac activity, in creased blood pressure, release lipids from adipose tissue

34
Q

pineal gland (l, s, t, e)

A

location - part of epithalamus, dorsal to hypothalamus; small, red, pinecone shaped
secretion - melatonin
targets - hypothalamus and anterior pituitary
effect - regulates circadian rhythms