Psychobiology part 2 unit 7 Flashcards

1
Q

What is a neuron, and why is it important?

A

Neurons are the basic functional units of the nervous system.
They form a vast network for processing and transmitting information, connecting up to 50,000 other neurons each.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name the key parts of a neuron and their functions.

A

Dendrites: Receive signals through synaptic receptors.
Cell body: Integrates incoming signals.
Axon: Transmits signals to other neurons, muscles, or organs.
Presynaptic terminal: Releases neurotransmitters to communicate with the next cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What does the neuron’s cell membrane do?

A

The cell membrane acts as a barrier, controlling the movement of ions like Na⁺ and K⁺, which is crucial for generating nerve impulses.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the resting potential of a neuron?

A

The resting potential is the difference in charge across the membrane at rest (~-70 mV).
Maintained by:
Sodium-potassium pumps (3 Na⁺ out, 2 K⁺ in).
Negatively charged proteins (A⁻) inside the cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What causes an action potential?

A

The threshold of excitation is reached (around -55 mV).

Depolarization: Na⁺ rushes in, making the inside positive.

Repolarization: K⁺ exits, restoring negativity.

Hyperpolarization: The cell briefly becomes more negative than at rest.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is saltatory conduction, and why is it efficient?

A

In myelinated axons, action potentials jump between nodes of Ranvier.
It speeds up conduction and conserves energy by limiting ion exchange to the nodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the resting potential, and how is it maintained?

A

Resting potential is the charge difference across the membrane at rest (~ -70 mV).
Maintained by:
Sodium-potassium pumps (3 Na⁺ out, 2 K⁺ in).
Negatively charged proteins (A⁻) inside the cell.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What triggers an action potential in a neuron?

A

When the membrane reaches the threshold of excitation (~-55 mV), Na⁺ channels open.
Na⁺ rushes in, causing depolarization and making the inside positive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Describe the key phases of an action potential.

A

Depolarization: Na⁺ enters, making the inside positive.
Repolarization: K⁺ exits, restoring the negative charge.
Hyperpolarization: The membrane temporarily becomes more negative than the resting potential.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How does the action potential travel along the axon?

A

Continuous conduction: In unmyelinated axons, the impulse moves as a wave.
Saltatory conduction: In myelinated axons, it jumps between nodes of Ranvier, making it faster.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the two types of refractory periods in a neuron?

A

Absolute refractory period: No action potential can occur.
Relative refractory period: A stronger stimulus can trigger an action potential.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the role of voltage-gated ion channels in neural impulses?

A

Na⁺ channels: Open during depolarization to allow sodium ions to enter.
K⁺ channels: Open during repolarization to allow potassium ions to exit.
Both are critical for generating and propagating the action potential.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are nodes of Ranvier, and what is their role in neural impulses?

A

Nodes of Ranvier are gaps in the myelin sheath along myelinated axons.
They allow the action potential to be regenerated by exposing the axon membrane to the extracellular fluid.
This enables saltatory conduction, where the action potential jumps between nodes, making signal transmission faster and more efficient.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the All-or-None Law in neural impulses?

A

The All-or-None Law states that a neuron either fires a full action potential or does not fire at all.
Once the threshold of excitation (~-55 mV) is reached, the action potential is generated with the same strength and speed regardless of the stimulus size.
A stronger stimulus does not produce a stronger action potential, but it may increase the frequency of firing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What role does K⁺ play in repolarisation?

A

K⁺ channels open, and potassium ions leave the cell, taking positive charges with them.
This movement makes the inside of the neuron more negative, restoring the resting potential.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Why does hyperpolarisation occur after repolarisation?

A

Hyperpolarisation happens because too much K⁺ exits the cell, making the membrane potential temporarily more negative than the resting potential.
This overshoot ensures proper resetting of the neuron.

17
Q

What is the refractory period, and why is it important?

A

The refractory period is the time after an action potential when the neuron cannot fire another signal.
There are two types:
Absolute refractory period: No action potential can occur.
Relative refractory period: A stronger stimulus can trigger an action potential.
It ensures signals move in one direction and prevents overfiring.

18
Q

How does Cl⁻ contribute to hyperpolarisation?

A

Chloride ions (Cl⁻) enter the cell when the inside is highly positive.
This increases the negative charge inside the cell, contributing to hyperpolarisation and resetting the neuron for its next signal.

19
Q

What are voltage-gated ion channels, and why are they important?

A

Voltage-gated ion channels open or close depending on the membrane potential.
Two key channels:
Na⁺ channels: Open during depolarisation to let sodium ions in.
K⁺ channels: Open during repolarisation to let potassium ions out.
These channels are essential for generating and propagating action potentials.

20
Q

How does the sodium-potassium pump help reset the neuron after an action potential?

A

The sodium-potassium pump restores the ion gradient by actively:
Pumping 3 Na⁺ out.
Pumping 2 K⁺ in.
This process restores the resting potential (~-70 mV) and prepares the neuron for the next action potential.

21
Q

Why is the action potential considered an all-or-none event?

A

If the stimulus reaches the threshold of excitation (~-55 mV), the neuron fires a full action potential.
If the threshold is not reached, no action potential occurs.
The strength of the stimulus does not affect the size or speed of the action potential.

22
Q

How does continuous conduction differ from saltatory conduction?

A

Continuous conduction:
Occurs in unmyelinated axons.
The action potential travels as a continuous wave along the axon.
Saltatory conduction:
Occurs in myelinated axons.
The action potential jumps between nodes of Ranvier, making it faster.

23
Q

What is depolarisation, and what triggers it?

A

Depolarisation occurs when the neuron becomes less negative (more positive) inside.
Triggered by the opening of voltage-gated Na⁺ channels, allowing Na⁺ to flow into the cell.

24
Q

What is propagation, and how does it occur?

A

Propagation is the movement of the action potential along the axon.
In unmyelinated axons, the action potential travels as a continuous wave.
In myelinated axons, it jumps between nodes of Ranvier (saltatory conduction), making the process faster and more energy-efficient.

25
Q

What is Multiple Sclerosis, and how does it affect neural impulses?

A

Multiple Sclerosis (MS) is an autoimmune disease that damages the myelin sheath in the CNS.
This disrupts saltatory conduction, slowing or blocking action potential propagation along axons.
Symptoms include muscle weakness, coordination issues, and cognitive impairment.