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Repodction > Psychiatric Disorders and Substance Abuse in Pregnancy AND DRUGS > Flashcards

Psychiatric Disorders and Substance Abuse in Pregnancy AND DRUGS Flashcards

1
Q

Approx half of suicides occur how long after giving birth?

A

Half suicides occur up to 12 weeks postnatally

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2
Q

Which condition predicts postnatal depression?

A

Anxiety

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3
Q

Why must you avoid benzos in pregnancy?

A

Can cause cleft lip/palate

Neonatal withdrawal

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4
Q

If you have bipolar, chances of baby being affected?

A

1 in 7

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5
Q

If mother has schizophrenia, what are the chances of child developing it?

A

10%

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6
Q

Which antipsychotics can you give for schizophrenia during pregnancy?

A

Haloperidol and

Chlorpromazine appear safe

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7
Q

Side effects of clozapine, olanzapine and risperidone in pregnancy?

A

Can cause gestational diabetes

IUGR

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8
Q

Anticholinergic drugs are often prescribed for extra-pyramidal symptoms, can they be used in pregnancy?

A

no

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9
Q

Effect of olanzapine in breastfed baby

A

Causes extra-pyramidal effects

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10
Q

Name 2 antipsychotics contraindicated in breast feeding

A

Clozapine

Lithium

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11
Q

If you prescribe haloperidol/chlorpromazine, what must you observe for in the baby?

A

Look for lethargy and sedation and whether they are reaching milestones or not

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12
Q

Complications of eating disorders in pregnancy?

A

IUGR, prematurity, hypokalaemia, hyponatraemia, metabolic alkalosis, miscarriage, premature delivery

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13
Q

Side effect of venlaxafine

A

Hypertension

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14
Q

Side effect of paroxetine

A

Cardiac abnormalities

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15
Q

Which anti-depressants pass into breast milk?

A

TCAs and SSRIs

-citalopram and fluoxetine especially (high levels)

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16
Q

Risk carries by all anti-depressants?

A

All antidepressants carry risk withdrawal or toxicity in neonates: usually self limiting and mild

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17
Q

Which TCAs are safe for pregnancy and breast feeding?

A

Amitryptiline and noritryptiline

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18
Q

When does post-natal depression start?

A

2-6 weeks after birth

19
Q

Which drug can cause ebsteins anomaly?

A

Lithium

20
Q

Which drug can lower IQ?

A

Valproate

21
Q

Associated with neural tube defects?

A

Valproate

22
Q

Can cause Steven-Johnsons syndrome if baby is breastfed while mother is on this drug

A

Lamotrigine

23
Q

When do baby blues occur?

A

Days 3-10

Self-limiting

24
Q

When does peurperal psychosis occur?

A

Usually presents within 2 weeks of delivery

25
Q

Alcohol advice during pregnancy?

A

RCOG suggests abstinence best but no evidence that 2 units/ week detrimental

26
Q

Risks of alcoholism in pregnancy?

A

Risks of miscarriage

FAS- facial deformities, lower IQ, neurodevelopmental delay, epilepsy, hearing, heart and kidney defects

Withdrawal

Risk Wernicke’s encephalopathy- 20% die (B1 deficiency)

Korsakoff Syndrome – permanent

27
Q

Fetal alcohol syndrome

A

facial deformities, lower IQ, neurodevelopmental delay, epilepsy, hearing, heart and kidney defects

28
Q

Teratogenic effects of cocaine, amphetamine and ecstasy?

A

Microcephaly

Cardiac, genitourinary, limb defects

29
Q

Effects of opiates in pregnancy?

A

IUGR
Neonatal withdrawal
Stillbirth
SIDS

30
Q

Effects of nicotine in pregnancy?

A 
Miscarriages
Abruption
IUGR
Stillbirth
SIDS
31
Q

When should hyperemesis resolve by?

A

Week 16

32
Q

If someone has puerperal psychosis, risk of relapse?

A

50%

33
Q

Can you let someone take diazepam in pregnancy?

A

LOL NO

-cause cleft lip and withdrawal

34
Q

Side effect of benzodiazepines in pregnancy?

A

Cleft lip and palate

Neonatal withdrawal

35
Q 
This drug can cause:
NTD
Craniofacial defects
CV abnormalities
Reduced IQ
Cleft lip/palate
Genitourinary Anomalies
A

Valproate

36
Q

This drug can cause finger nail hypoplasia

A

Carbamazepine

37
Q

Associated with vitamin K deficiency and haemorrhagic disease of the newborn

A

Carbamazepine

38
Q

This drug is associated with neonatal hypotonia,
hypothyroidism
hypoglycaemia

A

Lithium

39
Q

Methyldopa mechanism of action

A

Alpha agonist

40
Q

Labetalol mechanism of action

A

Alpha and beta agonist

41
Q

Nifedipine mechanism of action

A

Ca2+ blocker

42
Q

Hydralazine mechanism of action

A

Vasodilator

43
Q

Methyldopa is contraindicated in which condition?

A

Depression

44
Q

Labetalol is contraindicated in which condition?

A

Asthma

Repodction (52 decks)

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