Psych Flashcards

1
Q

SNRI

A

venlafaxine
duloxetine
desvenlafaxine

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2
Q

SNRI AE

A

anxiety and insomnia

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3
Q

TCA

A

doxepin
amitriptyline

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4
Q

TCA AE

A

increased QTc interval

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5
Q

buspirone AE

A

weaker, slower onset of action
do not use in anorexia or bulemia –> lowers seizure threshold

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6
Q

benzo AE

A

cognitive impairment
ataxia
withdrawal
abuse

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7
Q

GAD time criteria

A

> 6mo

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8
Q

panic disorder time criteria

A

3 panic attack episodes w/in 3wks

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9
Q

specific phobia time criteria

A

> 6mo

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10
Q

specific phobia tx

A

CBT w/ exposure therapy

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11
Q

social phobia time criteria

A

> 6mo

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12
Q

bipolar 1 criteria

A

manic at least 1wk

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13
Q

bipolar disorder 2 criteria

A

hypomanic, milder version of bipolar
4 days

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14
Q

lithium AE

A

check renal function (nephrotoxic)
nephrogenic DI, DMT2
hypothyroidism, tremor
Epstein’s anomoly (tricuspid valve abnormality)

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15
Q

if patient on lithium and pregnant, switch to

A

lamotrigine

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16
Q

valproate MOA and AE

A

increase GABA in brain
liver failure, pancreatitis
teratogenic neural tube defects

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17
Q

lamotrigine AE

A

SJS

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18
Q

carbamazepine AE

A

asplastic anemia
SIADH
teratogenic neural tube defect

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19
Q

bipolar tx

A

lithium
anticonvulsants: valproate, lamotrigine, carbamazepine
antipsychotics: quetiapine, lurasidone, olanzapine
benzo

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20
Q

quetiapine AE

A

increase mortality in elderly w/ demential related psychosis
suidical thoughts and behaviors

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21
Q

lursidone AE

A

increase mortality in elderly w/ demential related psychosis
suidical thoughts and behaviors

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22
Q

olanzapine AE

A

weight gain, DMT2
increase mortality in elderly w/ demential related psychosis
post injection delirium/sedation

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23
Q

strongest factor of bipolar disorder

A

FHx

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24
Q

depression screen

A

start in adolescents 12-18yo

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25
Q

cyclothymic disorder time criteria

A

at least 2y
not full hypomanic episode

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26
Q

MDD time criteria

A

> 5sx for at least 2wks

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27
Q

persistent depressive disorder (dysthymia) time criteria

A

at least 2yrs

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28
Q

PMDD time criteria

A

luteal phase
>5sx final week before menses

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29
Q

suicide risk factors

A

Sex male
Age (YA/elderly)
Depression
Previous attempt
Ethanol/drug use
Rational thinking loss (psychosis)
Sickness (medical illness)
Organized plan
No spouse or social support
Stated future intent

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30
Q

suicide highest RF

A

previous attempt

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31
Q

conduct disorder criteria

A

under 18yo
at least 3 behaviors over the past year and at least 1 occurring w/in past 6mo

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32
Q

oppositional defiant disorder criteria

A

at least 4 sx present > 6mo

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33
Q

oppositional defiant disorder tx

A

behavior mod
parent management training
rx if ADHD

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34
Q

Dissociative fugue

A

abrupt change in geographic location w/ inability to recall past, loss of identify

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35
Q

anorexia nervosa BMI

A

<17.5 or body weight <85% of ideal weight

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36
Q

anorexia nervosa labs

A

hyponatremia, hypokalemic
alkalosis if vomiting, arrhythmias (QT prolongation)
dec LH/FSH, dec estrogen/testosterone
hypothyroidism, hypoglycemia
osteopenia, anemia, inc BUN

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37
Q

anorexia indications for hospitalization

A

pulse <40, BP <80/60 or light headedness
orthostatic changes, hypothermia
refeeding syndrome
<70% expected weight or BMI <15
acute food refusal, suicidality, psychosis

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38
Q

refeeding syndrome sx

A

hypophosphatemia
dysrhythmia
severe edema

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39
Q

russels sign

A

bulimia
calluses on back of hands d/t induced vomiting

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40
Q

bulemia nervosa labs

A

hypochloremic
hypokalemic
metabolic alkalosis d/t vomiting

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41
Q

bulemia FDA approved tx

A

fluoxetine

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42
Q

binge eating disorder criteria

A

sx 1x/wk for 3mo

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43
Q

female sexual interest/arousal disorder criteria

A

3+ sx for 6mo that cause distress

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44
Q

impotence test

A

r/o med and rx causes
BIT: check for night time erections (postage stamp test)
if + night time erections = psych cause

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45
Q

tx impotence

A

PDE5 inhibitors (sildenafil)
vacuum device prosthetic
psychotherapy

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46
Q

paraphilia disorder criteria

A

sx for 6mo

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47
Q

OCD associated disorders

A

tourettes
tx w/ risperidone

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48
Q

ADD/ADHD criteria

A

at least 6 inattentive sx and/or at least 6 hyperactivity/impulsivity sx
sx present for >6mo in 2+ settings
onset usually <12yo

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49
Q

MC single genetic cause autism

A

fragile X syndrome

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50
Q

cluster A personality disorder

A

“weird”
schizoid
schizotypal
paranoid

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51
Q

cluster B personality disorder

A

“wild”
antisocial
borderline
histrionic
narcissistic

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52
Q

cluster C personality disorder

A

“wimpy”
avoidant
dependent
obsessive compulsive

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53
Q

brief psychotic disorder criteria

A

> 1 psychotic sx for <1mo

54
Q

schizophrenia criteria

A

2+ sx present for at least 1mo
continuous impairment for >6mo
significant functional decline

55
Q

tx schizophrenia

A

1st line: olanzapine, quetiapine, ziprazidone, risperidone
urine tox
refractory: clozapine
acute episode: hospitalization

56
Q

schizophreniform criteria

A

schizophrenia for >1mo and <6mo

57
Q

schizoaffective criteria

A

schizophrenia 2wks + mood disorder (MDD or manic)

58
Q

delusional disorder criteria

A

1+ delusions for at least 1mo
function not significantly impaired
does not meet criteria for schizophrenia

59
Q

cataplexy

A

loss of muscle tone following strong emotional stimulus

60
Q

narcolepsy sx

A

excessive daytime sleepiness
hallucination just before sleep or just before awakening
sleep paralysis

61
Q

narcolepsy test

A

polysomnography

62
Q

narcolepsy tx

A

first line: modafinil
scheduled naps

63
Q

restless leg disease test

A

polysomnography
nerve conduction studies

64
Q

restless leg disease tx

A

lifestyle
D/C offending meds
supplemental iron
1st line: dopamine agonist: pramipexole, ropinerole
benzo as adjunct
gabapentin

65
Q

somatic sx disorder criteria

A

1+ somatic sx (pain), distressing or resulting in significant disruption
no physical cause
>6mo

66
Q

somatic sx tx

A

regular visits w/ 1 PCP

67
Q

illness anxiety disorder sx and criteria

A

anxiety about health, hypochondriac
>6mo

68
Q

illness anxiety disorder tx

A

regular visits w/ 1 PCP

69
Q

factitious disorder sx

A

falsification of physical or psychological sx absence of obvious external rewards
repeated and long term hospitalization common

70
Q

malingering vs factitious disorder

A

malingering: external reward or secondary gain. not a mental illness
factitious: no obvious external reward

71
Q

alcohol use disorder tx

A

naltrexone: dec craving
acamprosate: for pts w/ liver dz or opioid use
disulfiram: 2nd line for highly motivated pts
thiamine, Mg (before dextrose), multivitamin, haloperidol if aggression

72
Q

disulfiram CI

A

CV dz, DM, epilepsy, hypothyroidism, kidney problems
can cause N/V

73
Q

alcohol withdrawal sx

A

6h
trembling, irritability
anxiety, HA, tachycardia

74
Q

alcohol withdrawal tx

A

IV thiamine w/ mg (before dextrose)
multivitamin, folate
IV fluids

75
Q

alcohol withdrawal seizure

A

48h, tonic clonic seizures
tx w/ benzo w/ taper (lorazepam)
head CT

76
Q

delirium tremens

A

48-96h
autonomic instability, disorientation, hallucination, agitation

77
Q

delirium tremens tx

A

thiamine –> glucose –> folate –> haloperidol (if psychosis)

78
Q

opioids

A

morphine
heroin
methadone
oxycodone
codeine

79
Q

opioids sx

A

pupil constriction (miosis)
euphoria and sedation
constipation, bradycardia, hypotension
respiratory depression, seizures, slurred speech

80
Q

opioid intoxication tx

A

naloxone

81
Q

opioid withdrawal sx

A

not fatal, anxiety, insomnia, anorexia, sweating
dilated pupils, piloerection
F, N/V, rhinorrhea, stomach cramps, diarrhea
flu-like sx

82
Q

opioid withdrawal tx

A

methadone, buprenorphine + naloxone
naltrexone (block cravings)
clonidine, loperamide, NSAID

83
Q

barbiturates sx

A

respiratory/CNS depression
depression, impaired memory, poor concentration
drowsiness

84
Q

barbiturates tx

A

sx management b

84
Q

barbiturates tx

A

sx management

85
Q

barbiturates withdrawal

A

anxiety, seizures, delirium
tx: long acting Benz w/ taper or phenobarbital

86
Q

benzo intoxication sx

A

amnesia, depression
ataxia, stupor, somnolence
minor respiratory depression

87
Q

benzo intoxication tx

A

flumazenil

88
Q

benzo withdrawal sx

A

rebound anxiety
seizures, tremor, insomnia

89
Q

benzo withdrawal tx

A

long acting benzo w/ taper (clonazepam/diazepam)

90
Q

amphetamines intoxication sx

A

AMS, euphoria, impaired judgement
delusion, hallucination, prolonged wakefulness/attention
agitaiton, pupil dilation, HTN, tachycardia, F, arrhythmia
violent behavior, psychosis, diaphoresis, choreiform movement, tooth decay

91
Q

amphetamines tx

A

haloperidol, bezo, vitC
propranolol for rate control

92
Q

MDMA (ecstacy) sx

A

hyperthermia, social closeness
“club drug”, hyponatremia

93
Q

MDMA tx

A

CCB

94
Q

do not give to MDMA intoxication

A

BB: cause coronary artery vasospasm

95
Q

cocaine intoxication sx

A

AMS, euphoria, agitaiton, hallucination, paranoid ideations
dec appetite, tachycardia, pupil dilation, HTN
angina (MI/CVA)
repetitive motions

96
Q

cocaine OD tx

A

haloperidol
benzo, vitC
labetalol

97
Q

cocaine withdrawal sx

A

severe depression, hyperphagia, hyper somnolence, fatigue
malaise, severe psychological craving

98
Q

cocaine withdrawal tx

A

bupropion, bromocriptine
SSRI for depression

99
Q

wernickes encephalopathy

A

triad: ataxia, confusion, oculomotor palsy (d/t thiamine deficiency)
from chronic ethanol or benzo intoxication

100
Q

Korsakoff syndrome

A

amnesia, hepatomegaly, palmar erythema
cirrhosis, dupuytrens contracture, gynecomastia
testicular atrophy
from chronic ethanol and benzo intox

101
Q

PCP intoxication sx

A

belligerence, impulsiveness, fear, homicidality
psychosis, delirium, seizures
nystagmus, tachycardia, ataxia

102
Q

PCP intoxication tx

A

benzos
haloperidol

103
Q

PCP withdrawal sx

A

depression, anxiety, irritability, restlessness
anergia, thought/sleep disturbances

104
Q

PCP withdrawal tx

A

sx tx

105
Q

LSD intoxication sx

A

visual hallucinations, seeing sound as color
anxiety/depression, delusions
pupil dilation, “bad trip panic”

106
Q

LSD intoxication tx

A

haloperidol
benzo

107
Q

cannabis sx

A

slowed perception, conjunctival injection
increased appetite, dry mouth

108
Q

cannabis withdrawal sx

A

peak in 48h, lasts 5-7d
irritability, depression, insomnia, N, anorexia, hyperemesis syndrome

109
Q

inhalants intoxication sx

A

belligerence, assertive, impaired judgement
apathy, blurred vision, coma

110
Q

inhalant intoxication tx

A

haloperidol

111
Q

anticholinergic toxicity sx

A

Hot as a hare: inc body temp
dry as a bone: dec secretions
red as a beet: flushed skin
blind as a bat: cycloplegia, mydriasis
mad as a hatter: AMS
full as a flask: urinary retention, constipation
fast as a fiddle: tachycardia

112
Q

adjustment disorder criteria

A

onset w/in 3mo
<6mo following termination of stressor

113
Q

PTSD criteria

A

sx >1mo

114
Q

acute stress disorder criteria

A

sx <1mo

115
Q

PTSD tx

A

CBT, SSRI
prazosin to reduce nightmares

116
Q

antipsychotics that have greatest risk of QTc prolongation

A

thioridazine
pimozide
droperidol
ziprasidone

117
Q

clozapine AE

A

agranulocytosis

118
Q

neuroleptic malignant syndorme sx

A

fever, confusion, muscle rigidity
rhabdo, autonomic instability (abn vitals, sweating)

119
Q

neuroleptic malignant syndrome tx

A

stop meds, supportive
dantrolene or bromocriptine (if refractory)

120
Q

tardive dyskinesia can be caused by

A

haloperidol
typical antipsychotic drugs (prolonged use)

121
Q

acute dystonia caused by

A

haloperidol
typical antipsychotic drugs

122
Q

acute dystonia sx

A

intermittent involuntary and uncoordinated hyperkinetic movements
spasm of tongue, neck, face, and back
sustained spasm

123
Q

acute dystonia tx

A

IM/IV benztropine or diphenhydramine

124
Q

serotonin syndrome sx

A

AMS, autonomic dysregulation (diaphoresis, tachycardia, HTN, hyperthermia),
neuromuscular hyperactivity (hyperreflexia, tremor, rigidity, babinski)
hyperactive bowel sounds, diarrhea

125
Q

serotonin syndrome tx

A

d/c drugs, supportive
cyproheptadine for severe cases
sedation w/ benzos

126
Q

meds that increase lithium levels

A

thiazide (HCTZ)
ACE (lisinopril)
NSAIDS
tetracyclines
metronidazole

127
Q

neonatal abstinence syndrome

A

withdrawal from opiates due to maternal drug use
neuro: irritability, hypertonia, jittery, seizures
GI: diarrhea, vomiting, feed intolerance
autonomic: sweat, sneeze, pupil dilation
tx w/ opioid therapy (morphine, methadone)

128
Q

normal grief

A

resolves w/in 1yr

129
Q

abnormal grief

A

severe sx
>1yr continued sx
positive suicide ideation

130
Q

persistent complex bereavement disorder

A

severe grief reaction >1yr (6mo in children) after death of bereaved