OBGYN Flashcards
breast abscess etiology
S. aureus
fibroadenoma vs fibrocystic changes
fibroadenoma doesn’t change w/ menstrual cycle
fibroadenoma tx
observation
US Q3-6mo
surgery if mass changes or enlarges
straw colored fluid on FNA bx
fibrocystic changes
1st line fibrocystic changes
OCP
Mild mastalgia: NSAIDS
Severe mastalgia: Tamoxifen or Danazol
galactorrhea tx
Tx underlying
Dopamine (bro/cab): decrease prolactin
levothyroxine: if hypothyroidism
MC med that cause gynecomastia
spironolactone
tx gynecomastia
testosterone replacement
tamoxifen
mastectomy
tx underlying
risk factor breast cancer
BRCA1 BRCA2
FHx, >70yo, never breastfed, OCP use
estrogen exposure (obese, nulliparity, early menarche, late menopause, late 1st pregnancy)
protective against breast cancer
breastfeeding
parity
MC location breast cancer
upper outer quadrant
breast cancer mammogram
microcalcifications
spiculated
guidelines breast cancer prevention
Mammo 50-74 q 2yrs (40-49 if high risk)
tx high risk of breast cancer
tamoxifen or raloxifene
cervical cancer screen
21-65 yo
21-29 Q3yrs
>30 Pap + HPV or Pap Q3yrs
MC cervical cancer
squamous
DES exposure
clear cell cervical cancer
clear cell vaginal cancer
Gardasil
HPV vaccine
start 11-12
<15 (2 doses, 6mo apart)
>15 (day 0, 2mo, 6mo)
cervical dysplasia management
Repeat pap Q6mo, colopscopy, return to routine screening
ASCUS: <30 repeat Q1yr, >30 + HPV colpo, >30 no HPV repeat Q3yrs
LGSIL: mild dysplasia, colpo if HPV, cytology in 1yr
HGSIL: mod/severe, colpo or loop, cytology in 6mo
missed abortion
abnormal US w/ no bleeding
no cervical dilation
threatened abortion
normal US w/ minimal bleeding
no cervical dilation
no POC
inevitable abortion
abnormal US w/ bleeding
dilated cervix, no POC
incomplete abortion
abnormal US w/ bleeding
dilated cervix, loss of some POC but not all
completed abortion
closed cervix
empty contracted uterus
abortion tx
curettage in 1st trimester or D&E in 2nd trimester
misoprostol
rhogam
MC RF placental abruption
HTN
cocaine user
placental abruption tx
stable and <34w: management w/ fetal monitoring
>36w: induction, oxytocin, vaginal delivery preferred
unstable: C section
variable deceleration and bradycardia in fetus
cord prolapse
tx cord prolapse
digital disengatement
knee to chest
C section
MC location of ectopic pregnancy
ampulla
ectopic pregnancy triad
unilateral pelvic pain
vaginal bleeding
amenorrhea
ectopic pregnancy tx
stable: monitor w/ HcG or MTX if identified later (<4cm), rhogam
unstable (hypotensive, tachycardia): laparoscopy
tx endometritis
C section: IV clindamycin w/ gentamicin
Vaginal delivery: ampicillin and gentamicin
prophylaxis 1st gen ceps during c section
gestational diabetes screen
24-28w increased fasting plasma glucose >125
initial: 1h OGTT (>140)
3h OGTT (>180 1h, >155 2h, >140 3h)= confirm
gestational diabetes tx
insulin TOC
metformin/glyburide (refuse insulin)
induce at 38w if uncontrolled, 40w if controlled
molar pregnancy dx
bhcg >100k
transvaginal US: snowstorm, cluster of grapes, honeycomb
molar pregnancy tx
D&C
rhogam
chemo if choriosarcoma (MTX)
do not give misoprostol, risk of incomplete uterine evacuation
1st line hypertensive meds in pregnancy
BB (labetalol)
CCB (nifedipine)
hydralazine
methyldopa
IV magnesium sulfate toxicity
hyporeflexia
tx w/ calcium gluconate
pregnancy induced HTN diagnosis
BP >140/90 after 20wks
tx preeclampsia
definitive: delivery
prophylaxis: ASA
prevention of eclampsia: IV mg sulfate + diazepam
tx eclampsia
IV mg sulfate + diazepam
definitive: delivery
HELLP syndrome
preeclampsia + hemolysis + increased LFT + low plt
tx HELLP
BP management
Mg sulfate
deliver if term
tx cervical insufficiency
No hx: vaginal progesterone (no hx)
hx: PO progesterone a + cerclage
no sex
CI in placenta previa
pelvic exam
preterm placenta previa tx
bed rest
tocolytics (mg sulfate)
CS
tx postpartum hemorrhage
uterine massage
oxytocin
misoprostol
PROM tests
+ fern test
+ nitrazine test (blue = ph > 6.5)
pooling of fluid in vaginal fornix
PROM tx
betamethasone/CS if <34w
delivery if >34w
preterm labor tx
tocolytics
CS
MG sulfate
Rh incompatibility sx
hydros fetalis
hemolytic anemia, jaundice, hepatosplenomegaly
kernicterus
rhogam when
28w
w/in 72h of delivery or potential mixing of blood
klinefelter syndrom karyotype
47XXY
heart defect assoc w/ klinefelter
MVP
klinefelter tx
testosterone for life
Turner syndrome karyotype
45X
heart defect assoc w/ turner syndrome
coarctation of aorta
tx turners syndrome
estrogen and progesterone substitution
tx infertility
clomid (ovulation inducer)
male: therapeutic insemination, intrauterine insemination
corrective surgery if occlusion
menopause labs
high FSH and LH
low estrogen/estradiol
secondary amenorrhea due to hypothalamus tx
normal or low FSH/LH
clomiphene
secondary amenorrhea due to pituitary tx
low FSH/LH, high prolactin
transphenoidal surgery
secondary amenorrhea due to ovarian etiology labs
high FSH
high LH
low estradiol
secondary amenorrhea criteria
menses absent for at least 3 cycles or 6 consecutive months
athletic triad
amenorrhea
fatigue (eating disorder)
osteoporosis
tx dysmenorrhea
NSAIDS
heat, exercise, OCP
laparoscopy if everything fails
tx DUB
leuprolide
anovulatory: OCP first line
acute severe bleed: high dose IV estrogen, high dose OCP
ablation: pt that dont want hysterectomy
hysterectomy definitive
PMS phase
must occur on 2nd half of menstrual cycle (luteal phase)
sx improve w/ menses
PMS tx
diet and exercise 1st line
SSRI
tx PMDD
1st line SSRI
tx ovarian cyst
asx= observation (<8cm), repeat US Q6wks
laparoscopy: >6cm
rupture: pain management, observation. laparoscopy to control hemorrhaging if unstable
triad PCOS
hirsutism, amenorrhea, obesity
PCOS US and lab
string of pearls
high testosterone, high DHEA
high LH/FSH >3:1
tx PCOS
weight loss
OCP mainstay
GYN cancer w/ highest mortality
ovarian cancer
chlamydia tx
azithromycin (pregnancy) or doxycycline (tx partner)
test for gono but no need to tx
lymphogranuloma venereum caused by
chlamydia trachomatis
tx gonorrhea
ceftriaxone tx chlamydia (azithromycin or doxycycline)
fitz hugh curtis syndrome
complication of PID
peri-hepatitis
violin string adhesions
glisson’s capsule surrounds liver
chandelier sign
PID
tx PID
outpt: ceftriaxone + doxy +/- metro
inpt: cefoxitin/cefotetan + doxy
congenital syphilis hallmark
hutchington teeth
syphilis sx
primary: chancre painless
secondary: rash palmes and soles, F, LAD, arthritis, hepatitis
tertiary: gummatous lesions, argyll robinson pupil, neurosyphilis
tx chancroid
azithromycin, rocephin
pregnancy systematic changes
hyperventilation (resp alk)
increased CO, dec peripheral resistance
high plasma vol, high RBC vol, hypercoagulable
inc GFR
AFP low, BHCG high, estradiol low
Down syndrome (trisomy 21)
when triple screen pregnancy
AFP, Bhcg, estradiol
15-20w
high AFP in triple screen
spina bifida or multiple gestation
low AFP, Bhcg, and estradiol
trisomy 18: stillborn or die w/in 1yr
misoprostol indication
induce labor, cervical ripening
terbutaline indication L&D
lung development
normal fetal HR
120-160 bpm
early decelerations on NST
compression of baby’s head
baby HR dec at same time as contractions
normal
late decelerations on NST
HR declines after contraction ends
uteroplacental insufficiency or fetal growth restriction
needs intervention
variable decelerations on NST
baby HR responding at different times
cord compression
needs intervention
abdominal size in pregnancy
12w: pubic symphysis
20w: umbilicus
36w: xiphoid process
group B strep screen during pregnancy
35-37w
endometriosis triad
cyclical premenstrual pelvic pain
dysmenorrhea
dysparenuria or dyschezia
endometriosis dx
laparoscopy w/ bx definitive: powder burn appearance
chocolate cyst
endometrioma
endometriosis tx
observation if asx
1st: laparoscopic ablation to preserve fertility
2nd: hysterectomy w/ oophorectomy
OCP/ NSAIDS 1st line
tx leiomyoma
asx observation w/ f/u q 6-12m
leupralide most effective
myomectomy if fertility desired
hysterectomy definitive
vaginal prolapse tx
kegals, pessary
surgery
MC endometrial cancer
adenocarcinoma
endometrial cancer dx
PAP w/ endometrial bx
endometrial stripe >4mm
tx endometrial cancer
total hysterectomy +/- rad
tx endometrial hyperplasia
1st line: progestin therapy, repeat bx in 3-6mo
atypical: hysterectomy
BV etiology
gardnerella vaginalis
atrophic vaginosis tx
vaginal or PO estrogen
MC vaginal cancer
squamous cell carcinoma
MC valvular cancer
SCC
APGAR score
appearance, pulse, grimace, activity, respiration
7+ normal
4-6: fairly low
<4 critically low