Practice Test Flashcards
macular degeneration hallmark
drusen bodies
central vision loss
affects detail and color vision
Charcot joint
destructive neuropathic joint arthropathy, assoc w/ DM
fleck fracture
fx at base of 2nd metatarsal
highly suspicious for lisfranc injury
PKD patients are at risk for
MVP, diverticulosis, berry aneurisms (subarachnoid hemorrhage)
stills murmur
mid systolic, musical, vibratory, noisy, high pitched murmur on inferior aspect of LLSB and apex
venous hum
grade 1 or 2 harsh systolic ejection murmur on LUSB
graham steell murmur
high pitched early diastolic murmur left sternal edge 2nd ICS w/ patient in full inspiration
assoc w/ pulmonary HTN
phenelzine can cause hypertensive crisis by combo with
tyramine containing foods (aged cheese and wines)
pill rolling tremor
shuffling gait with lack of arm movements
fixed facial expression
seborrhea of the skin
parkinson
Parkinson tx
levidopa/ carbidopa
first line tx idiopathic pulmonary fibrosis
CCB: reduces pulmonary arterial pressure
Menkel diverticulum from what embryonic structure
vitelline duct
isotrentinoin AE
teratogenic, psych AE, hepatitis, inc triglycerides, hypercholesterolemia
increased estrogen
increased LH, increased FSH
FH/LSH secreting pituitary adenoma
decreased estrogen, decreased LH, decreased FSH
hypothalamic or pituitary failure
mixing study results in no correlation of increased PTT
clotting factor inhibitor (antiphospholipid syndrome)
meds that can be used in severe hypercalcemia
furosemide
IV NS
calcitonin, bisphosphonates
legg calve perthes classic presentation
loss of abduction and internal rotation of leg
MC therapeutic agents that can be used intrapleurally for pleurodesis in recurrent malignant pleural effusions
bleomycin
diverticulitis MC site
sigmoid colon
anthrax causative agent
bacillus anthracis
Q fever causative agent
coxiella burnetii
chancroid causative agent
Haemophilus ducreyi
conn’s syndrome tx
spironolactone
protocol for chemical exposure in eye
irrigation -> check pH -> visual acuity
med that can decrease psychotic episodes in patients w/ resistance to 1st line meds
clozapine
blurring of optic disk w/ optic disk swelling + neurologic sx diagnosis
head CT to r/o cranial tumor
sarcoidosis tx
oral prednisone
dubin johnson syndrome labs
isolated direct (conjugated) bilirubinemia
isolated increased indirect bilirubin
gilbert syndrome
criggler najjar syndrome
poison ivy presentation
erythematous pruritic rash arranged in linear or streak like configurations (where plant made contact w/ skin)
tx urge incontinence
oxybutinin
tx stress incontinence
pseudoephedrine
dawn phenomenon
decreased insulin sensitivity from nightly surge in glucagon and cortisol during nighttime fasting (normal glu evening then increased during late night or early morning, elevated when awake)
somogyi effect
nocturnal hypoglycemia then rebound early morning hyperglycemia. normal evening glucose then early morning hypoglycemia then hyperglycemia when waking
pronator syndrome
median nerve compression at level of proximal forearm
best treatment modality for patient w/ neuroleptic malignant syndrome
bromocriptine
tx trigemical myalgia
carbamazepine
atrial flutter tx
CCB (verapamil)
mycobacterium avium complex tx
clarithromycin + ethambutol or rifampin
Test for lithium induced nephrogenic DI vs central DI
Arginine vasopressin challenge test
high dose dexamethasone suppression test
Cushing’s syndrome
fluid challenge test
suspected prerenal azotemia
PCA occlusion
visual hallucinations, ipsilateral cranial nerve deficits, comas, drop attacks
contralateral muscle weakness
acute anterolateral infarction PE
4th heart sound
empiric management bacterial meningitis
IV ceftiaxone + IV vancomycin
Bowen’s disease
SCC in situ: epidermal and dermal cells w/ large pleomorphic hyper chromatic nuclei
refractory ITP tx
splenectomy
patho of positive sx in schizophrenia
excess dopamine receptors in mesolimbic pathway
patho of negative sx of schizophrenia
dopamine dysfunction in mesocortical pathway
parkinson pathology
idiopathic dopamine depletion in substantial nigra
bilateral hilar lymphadenopathy, noncaseating granuloma
sarcoidosis
swollen painful LN in groin, axilla, and cervical w/ multiple flea bites. safety pin appearance
yersinia pestis
which cell isn’t affected by polycythemia vera
lymphocyte line
med that can cause hypokalemia
furosemide (loop diuretic)
most important RF for cervical carcinoma
HPV infx
1st line sickle cell crisis
IVF and oxygen
adrenocortical insufficiency ABG
metabolic acidosis
MMR vaccine CI
hx of HIV and CD4 of 100
PCP pneumonia presentation
immunocomp (CD4<200), F, dyspnea, O2 desat, extremely high LDH, bilateral diffuse interstitial infiltrates
PCP pneumonia tx
bactrim
hypermagnesemia presentation
decreased DTR
Panama, F, cough, anorexia, light red spotted maculopapular rash w/ photosensitivity and joint pain
rubella
COPD which pneumonia etiology
H. flu
abnormal gait, weakness leg > arm, abulia, urinary incontinence, which artery occluded
anterior cerebral artery occlusion
neuroleptic malignant syndrome sx
1-2wks after initiating or increasing dose of DA antagonist (1st gen antipsychotics)
autonomic instability, incontinence, hyper salivation, hyperthermia, lead pipe rigidity, hyporeflexia, possible rhabdo
serotonin syndrome sx
autonomic instability, tremors, hyperthermia
mydriasis, diarrhea, abdominal cramps
erythema marginatum
rheumatic fever: macular, erythematous nonpruritic enlarging annular rash w/ rounded sharp demarcated edges, no central clearing, blanches w/ pressure
erythema migrans
lyme, target appearance
erythema nodosum
painful erythematous inflammatory nodules on anterior shins. increased estrogen exposure (pregnancy), sarcoidosis, TB, fungal infx
erythema multiforme
type IV hypersensitivity reaction. dusty violet red purpuric macules w/ vesicles or bull in center (target appearance)
erythema infectiosum
5th disease, slapped cheek appearance
cryptococcus meningitis test
india ink
MC cancer for smokers
adenocarcinoma
huntington disease sx
behavioral changes, chorea, dementia
parkinsons sx
resting tremor. bradykinesia, rigidity
thoracid outlet syndrome test
adson test: loss of radial pulse when head is turned to the affected side
pheochromocytoma test
24h urine vanillylmandelic acid levels
aseptic (viral) meningitis CSF
increased WBC count, normal glu, lymphocytosis
etiology: enterovirus
causative agent hairy leukoplakia
EBV
Medication used for Parkinson pill rolling tremor in young patients
benztropine
auspitz sign
psoriasis: punctate bleeding spots when the plaques of psoriasis are unroofed
guttate psoriasis classic description
small erythematous discrete papules w/ fine scales
class 2 anti arrhythmic that blocks alpha 1, beta 1, and beta 2
carvedilol
labetalol
cardioselective BB that affect beta 1 receptor only
atenolol
metoprolol
nonselective BB that block beta 1 and beta 2
propranolol
nadolol
first line tx osteomyelitis w/ beta lactamase positivity
IV nafcillin
first line tx TTP
plasmapheresis
TOC tumor lysis syndrome from chemotherapy
allopurinol + IVF
ALS sx
difficulty swallowing, abn speech w/ hoarseness, progressive weakness. atrophic tongue w/ fasciculations, increased DTR, babinski sign w/ muscle atrophy on head neck and torso (mixed UMN/LMN sx)
mittelschmertz
ovulation pain: low abd or pelvic pain during ovulation
IT band syndrome sx
lateral knee pain and tenderness
runners MC
chondromalacia sx
anterior knee pain behind or around patella
hematuria test <40yo
UA and culture
hematuria test >40yo
cystoscopy
IV pyelogram
urine cytology
RF bladder cancer
white male, cyclophosphamide, pioglitazone, dye exposure, rubber and leather, schistosomiasis infx, chronic bladder infx
close PDA
indomethacin
keep PDA open
prostaglandins
aortic stenosis sx
pulses parvus et tarsus (weak and delayed pulse)
fixed cardiac output
aortic regurgitation sx
bounding pulses
wide pulse pressure
pyloric stenosis test
US
PTSD first line
paroxetine (SSRI)
first line tx for long term schizophrenia
olanzapine (2nd gen antipsychotic)
Parkinson patho
idiopathic depletion of dopamine in basal ganglia
EKG severe chronic bronchitis
negative QRS in lead 1, positive QRS lead AVF (RAD from hypoxemia)
longstanding systemic HTN or aortic stenosis EKG
depth in S wave V1 + height of R wave V6 >35mm
lansoprazole AE
macrocytic anemia
tx hepatitis C
pegylated alpha interferon + ribavirin
toxoplasmosis presentation
hx HIV, F, body aches, HA. ring enhancing lesion on CT
toxoplasmosis RF
cat exposure
patho psoriasis
keratin hyperplasia in stratum basale and spinous due to T cell activation
type 2 hypersensitivity in basement membrane
bulbous pemphigoid
autoimmune disruption of desmosome later
bulbous pemphigoid
MC benign ovarian neoplasm
dermoid cystic teratomas
endometrial hyperplasia tx
progesterone only if want to preserve possibility of fertility
hysterectomy if do not want to preserve fertility
chancroid etiology
H. ducreyi
thrombocytopenia classic presentation
petechiae
MC clinical presentation in sickle cell
episodic hematuria
dequervain (subacute) thyroiditis lab
positive ESR
smooth muscle antibodies
autoimmune hepatitis
cirrhosis
PANCA
UC, microscopic polyangiitis, primary sclerosing cholangitis, churg-strauss
anti mitochondrial antibodies
primary biliary cirrhosis
endomysial antibodies
celiac disease
streptomycin AE
ototoxic
nephrotoxic
myersons sign
parkinsons
tap bridge of nose causes sustained blink
lhermittes sign
MS, inc DTR
positive ice pack test
myasthenia gravis
myasthenia gravis sx
diplopia, ptosis, generalized weakness (including respiratory), bulbar weakness (slurred speech, dysphasia)
best med for lowering isolated triglycerides
fibrates
MC presentation sickle cell
dactylitis
rash associated w/ celiac
dermatitis herpetiformis
kawasaki tx
aspirin + IVIG
MC echo and blood culture findings in endocarditis (no IVDU)
streptococcus viridian’s
mitral valve
MC echo and blood culture findings in endocarditis w/ IVDU
S. aureus
tricuspid valve
med that can cause hypothyroidism
amiodarone
chlamydia pneumophilia sx
atypical sx
sinusitis
mycoplasma pneumoniae sx
bulbous myringitis
pharyngitis
klebsiella pneumoniae sx
alcoholics and debilitated patients
cavitary lesions
currant jelly sputum
lacunar infart sx
Hx HTN and DM. dysarthria, clumsy hand syndrome. punched out hypotenuse lesions near basal ganglia
MC intrinsic kidney injury in hospitalized patients
ATN: oliguria, inc BUN/Cr
epithelial cell or muddy brown casts
ATN
ATN MCC
prolonged prerenal azotemia
contrast dye
ahminoglycosides (gentamicin)
sunburst
hair on end appearance
osteosarcoma
glyburide MOA
sulfonylureas: stimulates pancreatic beta cell insulin release in non-glucose dependent fashion
MOA metformin
decreases hepatic glucose production with no effect on pancreatic beta cells (biguanides)
acarbose and miglitol MOA
delays intestinal absorption of glucose (alpha glucosidase inhibitors)
pioglitazone and rosiglitazone MOA
increases insulin sensitivity at peripheral receptor sites of adipose and muscle tissues (thiazolidinedione)
liraglutide and eventide MOA
lowers glucose by mimicking incretin (glucagon like peptide 1 agonst
CI use of MTX in ectopic pregnancy
serum hCG >5000
ruptured ectopic pregnancy
hx TB
presence of fetal heart activity
DOC narrow complex SVT
adenosine
MC etiology from deli meats and unpasteurized cheeses that is gram positive bacilli
listeria monocytogenes
listeria tx
IV ampicillin
anthrax sx
painless black eschar
widened mediastinum
Ludwig angina sx
swelling and erythema to upper neck and chin. pus on floor of mouth
Vincents angina
trench mouth: profuse gingival bleeding, severe gingival pain, interdental papilla w/ ulcerative necrosis
zofran MOA
serotonin antagonist
serotonin syndrome sx
tachycardia, BP fluctuations, hyperthermia, hyperreflexia, myoclonus, dilated pupils, agitation, hyperactive GI tract
serotonin syndrome tx
cyproheptadine
benzo (for hyperthermia)
MS CSF
increased oligoclonal bands
GBS CSF
high protein w/ increased WBC (polymorphonuclear neutrophils) w/ dec glucose
vibrio cholera sx
diarrhea, grey w/ no odor, pus, or blood. ingesting shellfish
salmonella sx
invasive diarrhea, bloody, pea soup colored
Zollinger Ellison syndrome test
gastrin secretin in gastronomes not inhibited by secretin
management of choice localized renal cell carcinoma
radial nephrectomy
L4 disc herniation sx
pain and paresthesia along anterior leg, weakness w/ ankle dorsiflexion, loss knee jerk reflex
S1 disc herniation sx
pain and paresthesia posterior calf and plantar surface of foot w/ weakness when plantar flexion, loss ankle jerk reflex, walking on toes harder than on heels
TOC mycoplasma pneumoniae
fluid filled blisters on TM
macrolide or doxy
if child <8yo, azithromycin
patients w/ coarctation of aorta usually has
bicuspid aortic valve
cyclophosphamide AE
hemorrhagic cystitis
increase risk of bladder cancer
cimetidine AE
CP450 inhibition, gynecomastia, impotence
septic arthritis tx for gram negative diplococcus
gonorrhea: IV ceftriaxone
PE classic presentation tests
westermarks sign
hamptons hump
mainstay tx long term for chronic asthma
inhaled fluticasone
screening test for SLE
ANA (not specific)
anti histone ab
drug induced lupus
medications that increase incidence of myasthenia gravis
gentamicin
BB, FQ, aminoglycosides
tx nosocomial pneumonia (HAP)
piperacillin/ tazobactam + gentamicin
+ ASO titers
post streptococcus glomerulonephritis
diphtheria tx
diphtheria antitoxin + penicillin
Tx pleural effusion
thoracentesis
meds that increase prolactin levels
1st gen antipsychotics (haloperidol)
organophosphate poisoning tx
atropine + pralidoxime
organophosphate poisoning sx
HA, muscle spasm, tremors, convulsions, visual changes, chest tightness. diffuse wheezing, sweating, lacrimation
echo from restrictive cardiomyopathy
diastolic dysfunction w/ dilation of both atria
HIV med associated w/ vivid dreams and neurologic disturbances
efaviranz
tx infectious mastitis
warm compress, dicloxacillin
continue to breastfeed
MCC myocarditis
viral (enteroviruses)
neurogenic shock hallmark
hypotension w/ bradycardia, decreased pulmonary capillary wedge pressure
brown recluse spider bite presentation
local burning at site then blanching with red halo around ischemic center -> hemorrhagic bullae -> eschar formation
AE beta blockers
fatigue, depression, impotence, masks sx hypoglycemia, hypotension, bradycardia, 2nd/ 3rd heart block, bronchospasm
first line tx acute active bleeding from esophageal varices
endoscopic ligation of bleeding vessel
treatment acute dystonia
diphenhydramine
acute dystonia sx
trismus, protruding of tongue, facial grimace, torticollis, difficulty speaking
paroxysmal nocturnal hemoglobinuria sx
hemolytic anemia, venous thrombosis of large vessels, pancytopenia
methimazole AE
myelosupression (agranulocytosis), hepatotoxicity
doxorubicin AE
dilated cardiomyopathy, alopecia, bone marrow suppression
biots breathing
irregular respirations, quick shallow breaths of equal depth w/ irregular periods of apnea (opioid induced respiratory depression)
PID tx
IV doxycycline + ceftriaxone
C diff colitis tx
metronidazole
PO vancomycin if severe
when to do percutaneous nephrolithotomy
stones >10mm, struvite stones, and stag horn calculi
first line myesthenia crisis
plasmapheresis
initial tx HIT
argatroban
thiazolidinedione AE
rosiglitazone and pioglitazone. cardiotoxicity, CHF, hepatotoxicity, fx
Tx hypotonic isovolemic hyponatremia
fluid restriction and tx underlying cause
test for syphilis in presence of chancre or condyloma
darkfield microscopy
test for nephrogenic DI from central DI
desmopressin stimulation test
low AFP, high bHCG, low estradiol
trisomy 21
high alpha fetoprotein in triple screen
neural tube defect
multiple gestation
underestimate gestational age
low alpha fetoprotein, low estradiol, low bHcG
trisomy 18
H shaped vertebrae
sickle cell anemia
tx warm antibody autoimmune hemolytic anemia
CS
tx lyme meningitis
ceftriaxone
glioblastoma multiforme hallmarks
non homogenous mass w/ hypotenuse variable ring of enhancement w/ surrounding edema w/ butterfly appearance if it crosses corpus callosum
medullary thyroid carcinoma secretes
calcitonin
herpes simplex virus associated encephalitis CSF
increased protein w/ normal glucose and increased lymphocyte count
class 1 anti arrhythmic that prolongs ventricular depolarization and refractory period
procainamide
other electrolyte imbalance associated w/ hypocalcemia
hypomagnesemia
meningiomas location
MC in convex of hemispheres and parasagittal regions. often attached to dura
light wisp of cotton to test corneal reflex evaluates which CN
CN 5: trigeminal
Test abdominal aortic aneurysm
abdominal US
TOC acute exacerbations of MS
IV high dose CS
TOC neisseria meningitis
IV penicillin G
ITP tx
IVIG in kids
CS in adults
MC indication for hysterectomy
leiomyomas
which med decrease progression of relapsing remitting form of MS
glatiramr acetate
clozapine 2 major AE
agranulocytosis
myocarditis
med given before surgery of pheochromocytoma
phenoxybenzamine (nonselective alpha blockers)
management nephrogenic DI
indomethacin
HCTZ
MC pathogen post op surgical sites
S. aureus
coal workers pneumoconiosis xray
small opacities in upper lung fields
silicosis xray
small round opacities throughout lungs
calcified hilar lymph nodes
asbestosis xray
interstitial fibrosis
thickened pleura
test intussusception
barium enema diagnostic and therapeutic
pathogen in stream water
dyspepsia, loose stool
giardia lamblia
congenital abnormality associated with tracheoesophageal fistula
esophageal atresia
pertussis tx
azithromycin or bactrim
dew drop on a rose petal
varicella
social phobia tx
SSRI
celiac test to confirm diagnosis
small bowel biopsy
test to confirm hepatitis B vaccination
anti- HBs (surface antibody)
transmural inflammation
crohns
increase incidence of hip dysplasia
first born
left hip
female, breech
myotome triceps and extension of arm
C7
warfarin clotting factors
2, 7, 9, 10
RF preeclampsia
multiple gestation, nulliparity, advanced maternal age, AA, obesity
medication that affects INR of patient taking warfarin
bactrim
venous hemorrhages, disk swelling, cotton wool spots, dark dusky retinal background
CRVO
pain when extend elbow, arm pronated, and extend fingers and wrist against resistance
lateral epicondylitis
pain from resisted pronation or flexion of wrist
medial epicondylitis
vaccine CI in patient undergoing chemo
MMR
antihypertensive med to avoid in asthma patients
non beta 1 selective BB (propranolol)
penicillin MOA
inhibits cell wall synthesis
MC malignant primary tumor of bone
osteosarcoma
cardiac biomarker that rises in 1-4h, peaks at 6-7h, and returns to normal after 24h
myoglobin
endometritis tx
clindamycin
gentamicin
MOA delays gastric emptying, stimulating pancreatic insulin response to glucose, reducing glucagon release after meals
liraglutide (GLP1)
reduce breakdown of endogenous GLP1, making higher levels of GLP1
DDP4
lesion right optic tract posterior to chiasm
left homonymous hemianopsia
RBBB + ST elevation in V1-V3
brugada syndrome
anti arrhythmic that inhibit T3 to T4 conversion
amiodarone
nerve root for patellar reflex
L3/L4
MC pathogen bullous myringitis
mycoplasma pneumonia
dacryostenosis tx
digital massage
lacrimal duct probing if persistent
metformin MOA
decreases hepatic glucose production and increases peripheral glucose uptake
suppurative complication of GAS pharyngitis
peritonsillar abscess
ligament injured in gamekeepers thumb
ulnar collateral ligament
sign associated w/ idiopathic intracranial HTN
papilledema
furosemide monitor for
hypokalemia
MRSA abscess tx
I&D + clindamycin
impairs absorption of iron, avoid immediately before or after taking
calcium
CI for use of stool DNA test for colorectal cancer
hx of IBD
tx outpatient diverticulitis
metronidazole and cipro
pain along joint line with deep squatting
meniscal injury
anti seizure med with AE gingival hyperplasia
phenytoin
MCC erectile dysfunction
vascular disease
post strep glomerulonephritis UA
RBC casts
MCC heart failure in US
coronary artery disease q