Protozoa--others Flashcards

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1
Q

Trypanosoma cruzi–disease

A
  • visceral infection
  • Chagas disease
    • dilated cardiomyopathy with apical atrophy
    • megacolon
    • megaesophagus
    • predominantly in South America
    • unilateral periorbital swelling (Romana sign) characteristic of acute phase
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2
Q

Trypanosoma cruzi–transmission

A
  • reduviid bug (“kissing bug”) feces
    • deposited in painless bite (much like a kiss)
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3
Q

Trypanosoma cruzii–diagnosis

A
  • Trypomastigote in blood smear
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4
Q

Trypanosoma cruzi–treatment

A
  • Benznidazole of nifurtimox
    • ​”Cruzing in my Benz, with a fur coat on”
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5
Q

Leishmania donovani–disease

A
  • visceral infections
  • Visceral Leishmaniasis (Kala-azar)
    • spiking fevers
    • hepatosplenomegaly
    • pancytopenia
  • Cutaneous leishmaniasis
    • skin ulcers
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6
Q

Leishmania donovani–transmission

A
  • sandfly
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7
Q

Leishmania donovani–diagnosis

A
  • macrophages containing amastigotes
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8
Q

Leishmania donovani–treatment

A
  • amphotericin B
  • sodium stiboglutamate
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9
Q

Trichomonas vaginalis–disease

A
  • sexually transmitted infections
  • Vaginitis
    • foul smelling, greenish discharge
    • itching and burning
    • do not confuse with Gardnerella vaginalis–gram variable bacterium assoc with bacterial vaginosis
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10
Q

Trichomonas vaginalis–transmission

A
  • sexual–cannot exist outside human b/c it cannot form cysts
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11
Q

Trichomonas vaginalis–diagnosis

A
  • trophozoites (motile) on wet mount
  • “strawberry cervix”
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12
Q

Trichomonas vaginalis–treatment

A
  • metronidazole for patient and partner (prophylaxis)
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