Protocolos de Reperfusión en ACV Flashcards

1
Q

FSC en Area Normal, Penumbra e Infarto (mL/100g/’)

A

≻ 55, 10-30, 0-10

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2
Q

¿Qué es el mismatch en imagenología en ACV?

A

es la falta de coincidencia entre un estudio de difusion (DWI) y perfusion (PWI) en un ACV: área de penumbra

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3
Q

cuantas neuronas se pierden por minuto en acv de gran arteria

A

1.9 millones

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4
Q

Resumen Protocolos segun tpo:

A

0-3h: TC → NINDS: rt-PA IV c/s DTS (I A)
3-4.5h: TC → ECASS III: rt-PA IV c/s DTS (I A)
4.5-6h o fracaso: TC + Angio y/o Mismatch → PROACT II: rt-PA IA (II B)
6-8h o fracaso: Trombectomía Intraarterial (?)
9h: DIAS-4: Desmoteplase (experimental)

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5
Q

Efectos rt-PA ≺ 3h s/HIC

A

mejor outcome 90d en 30%, sHIC 10X, sin ↑ Mortalidad

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6
Q

Criterios Inclusion trombolisis: NINDS y ECASS III

A

NINDS: ≥ 18a, NIHSS ≻ 4, s/HIC

ECASS III: 18-80a, NIHSS ≺ 25, ≺ 1/3 ACM, antec ACV + DM

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7
Q

AHA: Test Dg ACV

A
  • TC c/cte
  • HGT
  • Cr, ELP
  • ECG, Cardiolitos
  • P.Hemat
  • PBQ
  • TP/TTPK
  • SatO2
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8
Q

Protocolo NINDS: rt-TPA EV

A
  • 0,9 mg/kg hasta 90mg: 10% en 1’, 90% en 60’
  • Cntrl NIHSS / PA: c/15’ x 1h → c/30’ x 5h → c/ 1h x 18h
  • Meta PA: ≺ 180/105
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9
Q

Tpo puerta - aguja ideal

A

60 min

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10
Q

Eco Doppler Transcraneano: qué TIBI habla de riesgo de vasoespasmo

A

TIBI 4: Estenótico

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11
Q

Recanalización potenciada por Doppler Transcraneano: ¿es mejor ?

A

casi el doble de recanalización (En estudio)

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12
Q

Trombolisis intraarterial: ¿tiempo de ventana?

A

hasta 6 hrs

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13
Q

% de recanalizacion por técnica

  • espontanea
  • espontánea ≻ 24h
  • rt-PA IV
  • rt-PA IV + DTC
  • rt-PA IA
  • rt-PA IV + IA
  • Trombolisis mecanica (Stentriver)
A
  • 24%
  • 53%
  • 43%
  • 66%
  • 63%
  • 68%
  • 84%
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14
Q

Protocolo Trombolisis Intraceberebral: ≺ 3 hrs (1A)

A

1º TC
2º Protocolo NINDS (NIHSS ≻ 4)
3º rt-PA IN
4º reevaluar en 3m

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15
Q

Protocolo Trombolisis Intraceberebral: ≺ 4.5 hrs (1A)

A

1º TC
2º Protocolo ECASS III (NIHSS ≺ 25, ≺ 1/3 ACM, ≺80a)
3º rt-PA IN
4º reevaluar en 3m

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