PRL NMT Filarial Worms (TAA) Flashcards

1
Q

Filarial worms is part of the superfamily _____

A

Filarioidea

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2
Q

Habitat of filarial worms

A

Subcutaneous tissues
Lymphatic system
Deep connective tissue

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3
Q

2 medically important filarial species in the Philippines

A

Wuchereria bancrofti
Brugia malayi

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4
Q

Common name of Wuchereria bancrofti

A

Bancroft’s Filarial Worm

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5
Q

Common name of Brugia malayi

A

Malayan Filarial Worm

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6
Q

Intermediate host of Wuchereria bancrofti

A

Anopheles, Aedes, Culex

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7
Q

Intermediate host of Brugia malayi

A

Mansonia bonneae, Mansonia uniformis

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8
Q

T/F: Anopheles mosquito may also transmit B. malayi

A

T

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9
Q

Habitat of the adult W. bancrofti

A

Lower lymphatic

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10
Q

Habitat of the adult B. malayi

A

Upper lymphatic

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11
Q

Diagnostic stage of W. bancrofti and B. malayi

A

Microfilaria

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12
Q

Samples used for the diagnosis of W. bancrofti and B. malayi

A

Blood, Lymphatic fluid

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13
Q

Infective stage of W. bancrofti and B. malayi

A

L3 filiform

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14
Q

Mode of transmission of W. bancrofti and B. malayi

A

Skin penetration

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15
Q

Periodicity of W. bancrofti

A

Nocturnal

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16
Q

Periodicity of B. malayi

A

Periodic-nocturnal, subperiodic

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17
Q

Compare the cephalic spaces of W. bancrofti and B. malayi

A

W. bancrofti: 1:1
B. malayi: 2:1

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18
Q

Sheath affinity of W. bancrofti to Giemsa stain

A

Unstained

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19
Q

Sheath affinity of B. malayi to Giemsa stain

A

Stained-pink

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20
Q

Appearance of body nuclei of W. bancrofti

A

Regularly spaced

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21
Q

Appearance of body nuclei of B. malayi

A

Overlapping/irregular

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22
Q

Has 2 terminal nuclei

A

B. malayi

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22
Q

Compare the curved appearance of W. bancrofti and B. malayi

A

W. bancrofti: graceful curve
B. malayi: kinky/stiff

23
Q

T/F: stains that can be used for filarial worms include Giemsa, Wright, and Hematoxylin stain

A

F. Wright stain is discouraged for filarial womrs

24
Period of sexual maturity of filarial worms
6-12 months
25
Up to how many microfilariae per day can be produced by female worm?
50 000
26
In which stain is the sheath more observable?
Hematoxylin stain
27
Drug of choice for filarial worms
Diethylcarbamazine
28
When is blood collection for the diagnosis of filariasis done?
at night
29
Reagent for Knott's concentration technique
2% formalin
30
Pathology of adult filarial worms
Lymphatic filariasis Elephantiasis Hydrocele
31
Vector of Loa loa
Fly (Chrysops sp.)
32
Periodicity of Loa loa
Diurnal
33
Habitat of the adult Loa loa
Subcutaneous tissue, blood
34
Has nuclei that extends to the tip of the tail
Loa loa
35
Vector of Onchocerca volvulus
Fly (Simulium sp.)
36
Periodicity of O. volvulus
Nonperiodic
37
Habitat of adult O. volvulus
Subcutaneous nodule, subcutaneous tissue
38
Unsheathed filaria species
Onchocerca volvulus Mansonella ozzardi Mansonella perstans Mansonella streptocerca
39
Has nuclei that extend to blunt tip of tail
Mansonella perstans
40
Vector of M. perstans
Midge (Culicoides sp.)
41
Periodicity of M. perstans
Nonperiodic
42
Habitat of adult M. ozzardi
Body cavity, blood, skin
43
Vector of M. ozzardi
Midge (Culicoides sp.)
44
Periodicity of M. ozzardi
Nonperiodic
45
Habitat of adult M. perstans
Mesentery, blood
46
Has nuclei that extend to the tip of hooked tail
Mansonella streptocerca
47
Vector of M. streptocerca
Midge (Culicoides sp.)
48
Periodicity of M. streptocerca
Nonperiodic
49
Habitat of adult M. streptocerca
Subcutaneous, skin
50
Causes river blindness
Loa loa
51
Common name for Loa loa
African eye worm
52
Side effects of Diethylcarbamazine
Fever, chills, headache, dizziness, nausea and vomiting, itching, and joint pain
53
Has the same morphologic characteristics as W. bancrofti but has no sheath
O. volvulus
54
Filarial worms in dogs
Dirofiliaria immitis Dirofiliaria repens
55
Diagnostic for Fillarial Worms
1. Thick smears 2. Diethylcarbamazine Provocative Test 3. Knott's Technique 4. RDT - antigen/antibody