PreOp Meds: Scopolamine

Question 1

How does scopolamine work?

Answer 1

• Muscarinic Antagonist with central & peripheral effects.

Question 2

When do scopolamine patches need to be applied? When does concentration peak?

Answer 2

• Onset: 4 hours
• Peak concentration: 8-24 hours

Question 3

What is scopolamine dosing and where do the patches need to be applied?

Answer 3

• 140mcg priming & 1.5mg over the next 72 hours.
• Apply to post-auricularly or on the back

Question 4

What is scopolamine’s best indication?
What three adverse effects are most prevalent?

Answer 4

• Motion-sickness
• Mydriasis, sedation, & photophobia