Pharm Adjunct: BB1 Selective - Esmolol (Brevibloc) Flashcards
1
Q
Differentiate the clearance mechanisms of metoprolol and esmolol.
A
- Metoprolol = Hepatic
- Esmolol = Plasma cholinesterases
S10
2
Q
Differentiate the E½ of metoprolol and esmolol.
A
Metoprolol E½ = 3-4 hours
Esmolol E½ = 9 minutes
S10
3
Q
What β blocker would be used for treat intubation stimuli?
A
Esmolol
S14
4
Q
What are the onset and offset of esmolol?
A
Onset: 5 min
Offset: 10-30min
S14
5
Q
What is the initial dose for esmolol?
A
20-30mg IV
S14
6
Q
Caution should be taken when giving esmolol with which two conditions?
Why?
A
- Cocaine and/or epinephrine
- Can cause pulmonary edema and cardiac collapse
S14
7
Q
Which of the following drugs would you utilize for a post-carotid endarterectomy with a BP of 214/62 ?
Labetalol
Esmolol
A
Esmolol
Labetolol could drop the dBP too much.
S25
