PreOp Meds: PPI - Omeprazole and Pantoprazole Flashcards

1
Q

What is the maximum acid inhibition that can be achieved by omeprazole?
What is omeprazole’s dosing?

A
  • 66%
  • 40mg/100cc over 30min or PO >3hours prior to sx.
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2
Q

What are the most common side effects of omeprazole?

A
  • HA, agitation, & confusion (crosses BBB)
  • Bacterial overgrowth
  • N/V
  • Flatulence & abdominal pain
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3
Q

What are the benefits of pantoprazole over omeprazole?

A
  1. Better bioavailability & longer E½
  2. Fast: can be given 1 hour prior to sx.
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4
Q

What is pantoprazole dosing?

A
  • 40mg in 100mL over 2-15 minutes
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