PreOp Meds: Lorazepam (Ativan) Flashcards

1
Q

Of midazolam, diazepam, and lorazepam, which is the most potent sedative/amnestic?

A
  • Lorazepam
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2
Q

Which benzodiazepine has the slowest onset of action?

A
  • Lorazepam
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3
Q

When is peak effect seen with lorazepam?

A
  • 20-30 min with IV dose (1-4mg)
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4
Q

What is the E ½ time of lorazepam?

A
  • 14 hours
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5
Q

Which benzodiazepine’s metabolism is less dependent on CYP450’s?

A
  • Lorazepam (better drug for liver patients)
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6
Q

When is lorazepam most useful?

A
  • Post-operative sedation
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