Pharm Adjunct: BB1 Selective - Metoprolol (Lopressor) Flashcards

1
Q

Differentiate the clearance mechanisms of metoprolol and esmolol.

A
  • Metoprolol = Hepatic
  • Esmolol = Plasma cholinesterases

S10

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2
Q

Differentiate the E½ of metoprolol and esmolol.

A

Metoprolol E½ = 3-4 hours
Esmolol E½ = 9 minutes

S10

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3
Q

What is the dose of metoprolol?

A

1mg q5min
(Given in 5mg “blocks”)

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4
Q

What two PO formulations of metoprolol are there?

A
  • Metoprolol Tartate = multiple doses per day
  • Metoprolol Succinate = One dose per day

S13

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