Pharm Adjunct: BB1 Selective - Metoprolol (Lopressor) Flashcards
1
Q
Differentiate the clearance mechanisms of metoprolol and esmolol.
A
- Metoprolol = Hepatic
- Esmolol = Plasma cholinesterases
S10
2
Q
Differentiate the E½ of metoprolol and esmolol.
A
Metoprolol E½ = 3-4 hours
Esmolol E½ = 9 minutes
S10
3
Q
What is the dose of metoprolol?
A
1mg q5min
(Given in 5mg “blocks”)
4
Q
What two PO formulations of metoprolol are there?
A
- Metoprolol Tartate = multiple doses per day
- Metoprolol Succinate = One dose per day
S13