Pharm Adjunct: BB1 - Propanolol (Inderal) Flashcards
1
Q
What non-selective β-blocker has active metabolites and is generally shitty for anesthesia?
A
Propanolol
S10
2
Q
When propanolol is given, what effect lasts longer, negative inotropy or negative chronotropy?
A
Negative chronotropy (bradycardia) lasts longer
S11
3
Q
What is a possible reason why the heart rate slowing effects of propanolol last longer than the negative inotropic effects?
A
Possible β1 sub-receptor types (ex. β1A, β1B, etc.)
S11
3
Q
Propanolol will decrease the clearance of which two important anesthetic drug classes?
A
- Opioids
- Amide LA’s
d/t lower C.O. /HR
S11
