Pre-anes Tranquilizers/sed P2 (a2 agonists) Flashcards
Difference between an agonist and antagonist
Agonist: stimulates receptors
Antagonist: suppresses receptors
Transmitters of sympathetic NS (2)
Epinephrine (adrenaline) and norepinephrine
The two receptors that epinephrine or norepinephrine could stimulate
Beta receptors or alpha2 receptors
What stimulation of beta receptors causes
Fight or flight response
What stimulation of alpha 2 receptors does
Causes sedation, analgesia, bradycardia, hypotension, hypothermia
Alpha2- adrenoceptor agonists do what to the alpha 2 receptors
Stimulate (bind to them), stimulating their effects
Desirable effects of a2 adrenoceptor agonists
Sedation, analgesia
Because of how sleep an a2 adrenoceptor drug makes an animal, we can reduce the amount of gen anesthesia _____%
50-80%
How long a2 agonists analgesia lasts
<15-20min
Cardiac output (CO) refers to
Volume of blood flow to heart
Tidal volume
Volume of gas inhaled in one breath
Repressed peristalsis, an undesirable effect of a2 agonist drugs, causes what in cattle and what in dogs
Cattle: bloat
Dogs: gastric dilation (stomach becomes overstretched and rotated by excessive gas content)
Why you should be cautious around an animal sedated by a2 agonist drugs
Unpredictable, can become aggressive, decreased bite inhibition
Why a2 agonist drugs can increase blood glucose levels
Suppression of pancreas secretion of insulin (allows glucose to be used as energy)
Diuresis
Increased urination
