Picornaviridae Flashcards
Swine vesicular disease is excreted in
Feces
Diagnosis of swine vesicular disease
Rapid test to rule out FMD
RT-PCR
Transmission of Foot and Mouth Virus
Respiratory Aerosols
Direct Contact
Indirect Contact via Fomite
Diagnosis of Foot and Mouth Disease
Virus isolation and identification - vesicular fluid
Clinical sign of what picornavirus

Swine Vesicular Disease Virus
Clinical features of Swine Vesicular Disease
Sudden appearance of lameness
Vesicles appear at the junction between heel and coronary band
Lesions on snout, lips and tongue
+/- encephalomyelitis
Swine vesicular disease virus is transmitted to pigs by
Skin abrasions and mucosa by ingestion and inhalation
Foot and Mouth Disease Virus belongs to what picornavirus genus
Aphthovirus
Effective disinfectent for picornaviruses
Sodium carbonate
_________________
Stable in mucus and feces, and can withstand strong sunlight
First demontrated as filterable agents that caused disease in animals
Picornavirdiae
Picornavirus Genus Enterovirus
Ubiquitous and occur in all vertebrates
Swine Vesicular Disease
Polioencephalomyelitis
Clinical sign of what Picornavirus

Swine Vesicular Disease Virus
Swine Vesicular Disease Virus
Italy
Resistant to ambient temperature and sodium carbonate
Transmitted to humans in pork products
Pigs only natural host
T/F: Samples for Foot and Mouth Disease Virus can be taken for laboratory diagnostics without prior contact of authorities.
False
Replication of swine vesicular disease occurs where
Gastrointestinal tract
Food and mouth disease virus stability
Survies in milk, milk products and bone marrow
Picornavirus virion properties
Non enveloped
Single stranded
Positive sense RNA
Picornavirdiae - 8 genera
Aphtovirus
Teschovirus
Erbovirus
Heaptovirus
Enterovirus
Cardiovirus
Kobuvirus
Parechovirus
Clinical signs of foot and mouth disease in cattle and pigs
Excessive salivation
Vesicles on coronary bands and interdigital space
Lesions on teats
abortion
Foot and Mouth Disease Virus genome organization
Single large open reading frame
Picornavirus that does not enter cells through endocytosis
Poliovirus
Transmission of foot and mouth disease to humans
Very rare
Type O, C and A
Ingestion of unprocessed milk or dairy products
Clinical signs of foot and mouth virus in sheep and goats
Mild if any - fever, oral lesions, lameness