Orthomyxoviridae Flashcards

1
Q

Influenza C

A

Contains human and swine firuses that rarely cause disease

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2
Q

Influenza A

A

Contain human, equine, swine and domestic poultry viruses

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3
Q

Clinical sign of what Orthomyxovirus

A

Avian Influenza

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4
Q

Transmission of orthomyxoviruses in poultry

A

By ingestion and inhalation

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5
Q

Isavirus

A

Contains only Infectious Salmon Anemia Virus

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6
Q

Thogotovirus

A

Contain tick borne viruses which infect livestock and humans in Africa, Europe and Asia

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7
Q

Equine Influenza virus replicates in

A

Epithelial cells of the upper and lower respiratory tracts

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8
Q

Avian Influenza vireamia leads to

A

Multifocal lymphoid and visceral organ necrosis

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9
Q

Swine influenza virus is transmitted through

A

Aerosols

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10
Q

Diagonsis of Swine Influenza Virus

A

Sudden onset of clinical symptoms

Virus identification - deep nasal swab

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11
Q

Diagnosis of Equine Influenza Virus

A

Clinical Presentation

RT-PCR

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12
Q

Swine Influenza virus replicates in

A

Upper respiratory tract

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13
Q

Genetic Shift

A

Changes in antigenic set up due to reassortment of gene segements

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14
Q

Avian Influenza viruses replicate in

A

Intestinal and Respiratory Tract

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15
Q

Transmission of orthomyxoviruses in mammals

A

Aerosol, droplet and fomite transmission

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16
Q

Diagnosis of Avian Influenza Virus

17
Q

Orthomyxovirus virion morphology

A

Pleomorphic

Segmented genome

Two types of glycoprotein spikes

18
Q

T/F: Influenza virues are sensitive to heat, acidic pH and lipid solvents

19
Q

Influenza B

A

Contain human viruses

20
Q

Clinical signs of low pathogenic avian influenza

A

Cause upredictable losses do to decreased egg production

21
Q

Transmission of orthomyxoviruses in aquatic birds

A

Virus is shed in feces - fecal oral transmission

22
Q

Genetic Drift

A

Changes in antigenic setup due to point mutations - nucleotide substitution, deletion, insertions

23
Q

Clinical signs of High pathogenic avian influenza

A

Cause sudden death without symptoms

Cessation of egg production, lacrimation, diarrhea, edema, cyanosis, torticollis

24
Q

Why are pigs considered “mixing vessels” for influenza viruses

A

Because of their ability to become co-infected with both avain and human strains of influneza virus

25
Transmission of Thogotoviruses is by
Ticks - replication in both tick and mammal
26
Classification of Orthomyxoviruses is based on
The type of hemagglutinin and Neuraminidase \_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_ 16 possible hemagglutinin 9 possible neuraminidase
27
Symptoms of Swine Influenza Virus
Appears in many animals at the same time Fever Nasal Discharge May develop pneumonia and die
28
Most important viral respiratory disease of horses
Equine Influenza Virus
29
Avain Influenza Viruses are characterized as
Highly Pathogenic Low Pathogenic
30
Clinical signs of Equine Influenza Virus
Rapidly spreads Fever Reddening of nasal mucosa Conjunctivitis Serous nasal discharge Dry paroxysmal cough Abortion
31
Transmission of Isavirus
Transmitted in water